DNA methylation

R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… Alu elements, and such sequences are methylated in the DNA of differentiated cells. In fact,
the … , unmethylated human L1 elements transpose at a higher rate in transfected human cells,…

DNA methylation and human disease

KD Robertson - Nature Reviews Genetics, 2005 - nature.com
… insights into how DNA methylation patterns are … DNA methylation patterns in human diseases.
It should be noted that I focus only on those diseases for which defective DNA methylation

Dynamic DNA methylation across diverse human cell lines and tissues

KE Varley, J Gertz, KM Bowling, SL Parker… - Genome …, 2013 - genome.cshlp.org
… -base resolution DNA methylation profiling on a diverse collection of 82 human cell lines
and … This study provides an atlas of DNA methylation across diverse and well-characterized …

A DNA methylation atlas of normal human cell types

N Loyfer, J Magenheim, A Peretz, G Cann, J Bredno… - Nature, 2023 - nature.com
… as clinical diagnosis based on circulating cell-free DNA methylation. Methylation atlas of
human cell types To portray genome-wide DNA methylation across a variety of cell types, we …

DNA methylation and healthy human aging

MJ Jones, SJ Goodman, MS Kobor - Aging cell, 2015 - Wiley Online Library
DNA methylation do not distinguish between them, and so for the purposes of this review, all
such modifications to DNA will be referred to as ‘DNA methylation… between DNA methylation

A systematic profile of DNA methylation in human cancer cell lines

MF Paz, MF Fraga, S Avila, M Guo, M Pollan… - Cancer research, 2003 - AACR
… the DNA methylation profile obtained in the current study would allow the classification of
human … and cellular types were not known to the researcher. We then proceeded to cluster the …

Extent of DNA methylation in human tumor cells

ES Diala, MSC Cheah, D Rowitch… - Journal of the National …, 1983 - academic.oup.com
… of DNA methylation in human cancer cells, we thought it most pertinent to measure the extent
of total genomic DNA methylation in cell lines derived from a diverse set of human tumors. …

DNA methylation age of human tissues and cell types

S Horvath - Genome biology, 2013 - Springer
… I propose that DNA methylation age measures the cumulative effect of an epigenetic
maintenance system. This novel epigenetic clock can be used to address a host of questions in …

Comparison of methods for quantification of global DNA methylation in human cells and tissues

S Lisanti, WAW Omar, B Tomaszewski, S De Prins… - PloS one, 2013 - journals.plos.org
… An overview of the absolute values for measures of genomic DNA methylation in the human
cells and tissues obtained using the 4 different techniques tested in this study is given in …

Studies of X chromosome DNA methylation in normal human cells

SF Wolf, BR Migeon - Nature, 1982 - nature.com
… The variety and instability of X DNA methylation patterns observed in normal human cells
may explain our inability to reactivate loci on the inactive X chromosome with 5-azaC. Because …