DNA methylation and gene expression

A Razin, H Cedar - Microbiological reviews, 1991 - Am Soc Microbiol
cells. The inactivation of only one allele in these cells presumably involves DNA methylation,
… In vitro correction of GT mispairs to GC pairs in nuclear extracts from human cells. Nature (…

DNA methylation and epigenetic mechanisms

R Holliday - Cell biophysics, 1989 - Springer
… plays an important role in the control of gene activity in cultured mammalian cells, and the …
DNA methylation are described. Human diploid cells progressively lose cytosine methylation

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

J Sandoval, H Heyn, S Moran, J Serra-Musach… - Epigenetics, 2011 - Taylor & Francis
… First, we compared the DNA methylation profiles of two human primary normal colorectal
mucosa samples with that observed in a widely used colorectal cancer cell line, HCT116. …

DNA methylation is a reversible biological signal

S Ramchandani, SK Bhattacharya… - Proceedings of the …, 1999 - National Acad Sciences
… The pattern of DNA methylation plays an important role in regulating different … DNA
methylation is a reversible biochemical process, we purified a DNA demethylase from human cells

The DNA methylation landscape of human early embryos

H Guo, P Zhu, L Yan, R Li, B Hu, Y Lian, J Yan, X Ren… - Nature, 2014 - nature.com
DNA methylation maps of human early embryos, we performed reduced representation
bisulphite sequencing (RRBS) on human … The methylation profiles form four distinct clusters …

DNA methylation and cancer

RL Momparler, V Bovenzi - Journal of cellular physiology, 2000 - Wiley Online Library
… Although these aspects of DNA methylation are very interesting, they are not discussed here
because … Identification of DNA methylation markers for human breast carcinomas using the …

Repairing DNA-methylation damage

B Sedgwick - Nature reviews Molecular cell biology, 2004 - nature.com
… meA)-DNA-glycosylase and O 6 -methylguanine (O 6 -meG)-DNA-methyltransferase enzymes
from bacteria, yeast and human cells … of DNA-methyltransferases in protecting human cells

DNA methylation and cancer

PW Laird, R Jaenisch - Human molecular genetics, 1994 - academic.oup.com
… evidence obtained in our laboratory with cells and mice homozygous for a … cells can be
attributed to the known MTase enzyme only if it is capable of such de novo DNA methylation

[HTML][HTML] Defining driver DNA methylation changes in human cancer

GP Pfeifer - International journal of molecular sciences, 2018 - mdpi.com
Human malignant tumors are characterized by pervasive changes in the patterns of DNA
methylation. These … It has been challenging to link specific DNA methylation changes with …

The effect of DNA methylation on gene regulation of human papillomaviruses

F Rösl, A Arab, B Klevenz… - Journal of general …, 1993 - microbiologyresearch.org
DNA methylation on transcriptional regulation of HPV, we examined the effect of in vitro
methylationmethylated HPV DNA in cervical carcinoma cells. Evidence is provided that in vitro …