… Finally, to gain insights into the biological roles of DNA methylation in somatic cells, we asked
if methylated CpG-rich promoters in primary fibroblasts regulate genes involved in specific …

… as DNA … DNA methylation in human cells, we chose a commonly used antidepressant,
citalopram, and analyzed its effects on human cells by performing genome-wide DNA methylation …

… To provide an introduction to the concept of DNA methylation and its function in normal cells,
… DNA methylation patterns of the calcitonin gene in human lung cancers and lymphomas. …

… be differentially methylated in humans (Chandler et ul., 1987). These experiments showed
unequivocally that the two rus alleles present in human cells can bear different methylation …

… genome DNA methylation analysis was done in different human cell types and the results
organised as a heatmap, with blue indicating low and yellow indicating high DNA methylation (…

… DNA methylation-associated silencing of tumor suppressor miRNAs contributes to the
development of human … , we studied the DNA methylation status of miR34b/c in human lung …

… 7 DNA methylation has also been directly implicated in genomic imprinting and X chromosome
inactivation.8,9 However, DNA methylation … the DNA methylation status in primary human …

… alter the catalytic domain of DNMT3B indicates that normal levels of DNA methylation in
humans are important for regulating expression of certain genes involved in differentiation. …

… Here we review recent findings on altered DNA methylation in human disease, with
particular focus on cancer and the increasingly large number of genes subject to tumor-specific …

… Recently, it has been reported that DNMT3B4 functions as a negative regulator of DNA
methylation in human hepatocellular carcinoma (HCC) cells [56 , 97, 122]. DNMT3B4 can bind to …