Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

J Sandoval, H Heyn, S Moran, J Serra-Musach… - Epigenetics, 2011 - Taylor & Francis
… 450K DNA methylation array can consistently and significantly detect CpG methylation changes
in … mucosa or HCT-116 cells with defective DNA methyltransferases (DKO). The provided …

Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

S Moran, C Arribas, M Esteller - Epigenomics, 2016 - Taylor & Francis
… Results & conclusion: The 850K array demonstrates high reproducibility at the 450K CpG
sites, is … as a useful tool for the analysis of the DNA methylation profile of the human genome. …

Review of processing and analysis methods for DNA methylation array data

CS Wilhelm-Benartzi, DC Koestler, MR Karagas… - British journal of …, 2013 - nature.com
… in the processing and analysis of array-based DNA methylation data and a summary of the
DNA methylation array-based platforms, thereby advancing our understanding of human

[HTML][HTML] Exploring the utility of human DNA methylation arrays for profiling mouse genomic DNA

NC Wong, J Ng, NE Hall, S Lunke, M Salmanidis… - Genomics, 2013 - Elsevier
… We investigated the use of human DNA methylation arrays … that these arrays can identify
differential DNA methylation in … mouse DNA methylation using the Human Methylation

Population-specificity of human DNA methylation

HB Fraser, LL Lam, SM Neumann, MS Kobor - Genome biology, 2012 - Springer
… of DNA methylation at over a third of all genes. Furthermore, although the methylation at over
… This showed excellent concordance with our array-based results (r 2 = 0.88 for IGSF2 and …

[HTML][HTML] High density DNA methylation array with single CpG site resolution

M Bibikova, B Barnes, C Tsan, V Ho, B Klotzle, JM Le… - Genomics, 2011 - Elsevier
… To assess the overall functionality of the individual CpG assays on HumanMethylation450,
we created three human genomic DNA methylation reference standards: unmethylated (U, 0%…

Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome

A Noguera-Castells, CA García-Prieto… - Epigenetics, 2023 - Taylor & Francis
… Herein, we have technically and biologically validated the new methylation array to show
its … methylome and thereby advancing our understanding of human DNA methylation

High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array

H Hayashi, G Nagae, S Tsutsumi, K Kaneshiro… - Human genetics, 2007 - Springer
… (CGIs) containing recognition sites of methylation-sensitive restriction enzymes. Here, we …
of DNA methylation using oligonucleotide tiling arrays. The input material is methylated DNA

DNA methylation and healthy human aging

MJ Jones, SJ Goodman, MS Kobor - Aging cell, 2015 - Wiley Online Library
… In terms of technology, the Illumina 450K array is the current gold standard for DNA methylation
arrays, but it has limitations in terms of genomic coverage at regions that may potentially …

Quantitative cross-validation and content analysis of the 450k DNA methylation array from Illumina, Inc.

J Roessler, O Ammerpohl, J Gutwein, B Hasemeier… - BMC research …, 2012 - Springer
DNA from 4 human breast cancer cell lines (IPH-926, HCC1937, MDA-MB-134, PMC42)
and 18 human … epithelial fractions was analyzed on 450k DNA methylation arrays. The β-values …