… DNA methylation is an important form of epigenetic … DNA methylation maps of human
early embryos, we performed reduced representation bisulphite sequencing (RRBS) on human …

… Here, we report on the DNA methylation landscape using the 450k array of four human …
The DNA methylation landscape of human fetal development provides insight into regulatory …

… human studies indicate that the methylation state can be influenced by the environment of the
early embryo, suggesting a potential role for methylation … dynamics in the early embryo, we …

… early embryonic landscapes are conserved 8,9,10 . We present genome-scale DNA methylation
maps of human … methylation landscape, with sperm and fetal tissue forming a somatic …

… of DNA methylation and aneuploidy in early human and … regulating gene expression in
the early embryo, as well as … free of DNA methylation in the early embryo correspond to …

… In this study, we systematically investigated the DNA methylation state of most human
autosomal CpGs to determine those that show dynamic changes and hence may participate in …

… DNA methylation levels in human early embryos. (a) The heat map of DNA methylation of
pre- and post-implantation human … status of DNA methylation during human early embryonic …

… The Dynamics of DHSs during Human Early Embryogenesis To investigate the chromatin
regulatory landscape in human early embryos, we collected the embryos at the two-cell, four…

… DNA through a maintenance DNA methylation mechanism during cell proliferation (Box 2).
Both de novo DNA methylation and maintenance DNA methylation … ) mouse embryos show …

… (Figure 2A) provides a mechanism that may contribute to DNA methylation pattern
dynamics in the early embryo [10,11], normal cell biology [12,13] and in disease processes [14]. …