… Since we studied organ biopsies similar to previous studies investigating biopsies of human
adult tissues [3,15], the methylation profiles we report reflect the average of multiple cell …

… In the present study we performed array-based methylation profiling on an extensive series
of fetal samples with normal and aberrant karyotypes obtained by routine prenatal CVS and …

… baseline understanding of tissue-specific variation in DNA methylation profiles of the … tissue
and Wharton jelly derived from the umbilical cord. The rationale for selecting these tissues is …

… Unrelated studies have demonstrated that in vitro culturing media alters DNA methylation
profile and gene expression in cell lines and mouse embryos [73,91]. Interestingly, a study …

… fetal liver or the bone marrow. By analyzing DNA methylation values at 402,819 tested
CpGs in fetal and adult erythroblasts, we identified 5,937 differentially methylated CpGs. These …

… -wide DNA methylation profiles of human somatic tissues. Although the number of analyzed
individuals was limited, the analysis was sufficient to provide DNA methylation distribution …

… We profiled DNA methylation (DNAm) in five fetal tissues ascertained from cases of NTDs
in British Columbia, a folate replete population, to test whether abnormal DNAm was a feature …

… The hypothesis that variation in the DNA methylation profile of human term placenta can serve
… demonstrated a pattern of methylation of 22 critical loci in human term placentas. Specific …

… In the present study, we compared the genome-wide methylation profiles of fetal tissues …
IVF-ET (embryo transfer) using an Illumina Infinium Human Methylation 450k BeadChip. We …

… In this study, we compare DNA methylation and gene expression from liver tissue of human
fetal and … Several studies have also shown changes in the profile of miRNAs during liver …