… of genomic CpGs changes its methylation … DNA methylation state of most human autosomal
CpGs to determine those that show dynamic changes and hence may participate in genome …

… Our MiGS data describe the DNA methylation patterns in the entire genomes of these cell …
previously known DNA methylation and identified numerous novel DNA methylation sites. Our …

… First, we compared the DNA methylation profiles of two human primary normal colorectal
mucosa samples with that observed in a widely used colorectal cancer cell line, HCT116. …

… The capillary sequencer is the main workhorse of the Human Genome Project. It does not
require radiation and polyacrylamide gel electrophoresis as initially invented by Frederick …

… the human genome in the K562 immortalized human cell line. … involved in DNA
methylation-mediated gene regulation and … inter-individual variation in DNA methylation is more …

… on methylation that occurs in CpG dinucleotides Despite being a key regulator of genomic
function, the role of DNA methylation … duplication events in the human genome. Though most …

… to natural human variation. To determine their contribution to variability, we have generated
genome-scale DNA methylation profiles of three human … methylated CpG sites. The distinctly …

… DNA methylation at cis-regulatory regions and its impact on gene expression, we measured
methylation… modifications at 16,000 promoters in primary human somatic and germline cells. …

… With the completion of the Human Genome Project, we … gene expression and DNA methylation
patterns. Below, I discuss several human diseases for which the role of aberrant genomic …

… the known effect of DNA methylation on mutation rate, our results suggest an interesting
interdependence between genetics and epigenetics underlying diversity in the human genome. …