[HTML][HTML] Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation

J Zhou, RL Sears, X Xing, B Zhang, D Li… - BMC genomics, 2017 - Springer
… averages are similar to those previously published for human and mouse [… human [33] and
mouse [34] and we find the global average CpG DNA methylation levels of our mouse and rat

Tissue-specific differences in DNA methylation in various mammals

MA Gama-Sosa, RM Midgett, VA Slagel… - … et Biophysica Acta (BBA …, 1983 - Elsevier
… differences in overall levels of human DNA methylation and the extent of transcriptional …
of DNA methylation in eucaryotes, we have analyzed the 5-methylcytosine content of DNA for …

Homocysteine and DNA methylation: a review of animal and human literature

PR Mandaviya, L Stolk, SG Heil - Molecular genetics and metabolism, 2014 - Elsevier
… to DNA methylation. Apart from this, a few studies investigated the effect of Hcy-lowering
trials on restoring DNA methylation … models as well as humans were included in this review. …

The impact of metabolism on DNA methylation

CL Ulrey, L Liu, LG Andrews… - Human molecular …, 2005 - academic.oup.com
… the study, folate-deficient rats had increased genomic DNA methylation in the colon.
Folate/… in male rats with the associated paradoxical hypomethylation of hepatic DNA and …

DNA methylation in aging of mice

RP Singhal, LL Mays-Hoopes, GL Eichhorn - Mechanisms of ageing and …, 1987 - Elsevier
… than unfractionated DNA. They also studied the tissue-specific variation in DNA methylation
and the intragenomic distribution of mSdC content in human DNA. Their results indicate …

DNA methylation

R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… sites contain methylated cytosines in most vertebrates, including humans.10,12 These
methylated regions are typical of the bulk chromatin that represents the late replicating DNA with …

DNA methylation and childhood maltreatment: from animal models to human studies

PE Lutz, G Turecki - Neuroscience, 2014 - Elsevier
… We review here both animal and human studies indicating that the epigenetic mechanism
of … examined DNA methylation in the exon 1 F of the GR gene, the human homolog to the rat

DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease

JV Sanchez-Mut, E Aso, N Panayotis, I Lott, M Dierssen… - Brain, 2013 - academic.oup.com
… For that, we designed a custom Illumina VeraCode DNA methylation mouse array enriched
in genes related to sensory perception, cognition, neuroplasticity, brain physiology and …

Biological significance of DNA methylation in the ageing process

T Ono, Y Uehara, A Kurishita, R Tawa… - Age and …, 1993 - academic.oup.com
… The change in DNA methylation could last for a long period of … in DNA methylation, however,
is not well understood yet. In order to clarify whether or not the change of DNA methylation

Methyl groups in carcinogenesis: effects on DNA methylation and gene expression

E Wainfan, LA Poirier - Cancer research, 1992 - AACR
… changes in patterns of methylation within the sequences specifying these genes. Changes
in DNA methylation and in gene expression induced in livers of rats fed MDD for 1 month …