DNA methylation in human sperm: a systematic review

F Åsenius, AF Danson, SJ Marzi - Human reproduction update, 2020 - academic.oup.com
… of cost-effective methods of interrogating DNA methylation, this premise has led to an … DNA
methylation landscape of human spermatozoa. However, how the human spermatozoal DNA

Intra‐and inter‐individual differences in human sperm DNA methylation

E Dere, S Huse, K Hwang, M Sigman… - …, 2016 - Wiley Online Library
… evidence that sperm DNA methylation is important in maintaining proper sperm health and
… that sperm DNA methylation levels are relatively stable between semen sample collections. …

Influence of global sperm DNA methylation on IVF results

M Benchaib, V Braun, D Ressnikof… - Human …, 2005 - academic.oup.com
… the relationship between sperm DNA methylation level and … The DNA methylation level
was then quantified by flow … embryos was correlated with the DNA methylation level (r=−…

[HTML][HTML] Exposure to childhood abuse is associated with human sperm DNA methylation

AL Roberts, N Gladish, E Gatev, MJ Jones… - Translational …, 2018 - nature.com
DNA methylation in gametes. We examined the association of childhood abuse with DNA
methylation in human spermDNA methylation was assayed in 46 sperm samples from 34 men …

[HTML][HTML] Decreased fecundity and sperm DNA methylation patterns

TG Jenkins, KI Aston, TD Meyer, JM Hotaling… - Fertility and sterility, 2016 - Elsevier
… In an effort to better understand the links between pregnancy and gamete quality, we
have analyzed a critical portion of the sperm epigenome, sperm DNA methylation. This is an …

Sperm global DNA methylation level: association with semen parameters and genome integrity

D Montjean, A Zini, C Ravel, S Belloc, A Dalleac… - …, 2015 - Wiley Online Library
… level was not related to sperm vitality or morphology. Our findings … sperm DNA methylation
levels are related to conventional sperm parameters, as well as, sperm chromatin and DNA

[HTML][HTML] Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm

S Houshdaran, VK Cortessis, K Siegmund, A Yang… - PloS one, 2007 - journals.plos.org
… To assess sperm DNA methylation at a … DNA methylation in ejaculated spermatozoa,
interrogating sequences in repetitive elements, promoter CpG islands, and differentially methylated

[HTML][HTML] Quantitation by image analysis of global DNA methylation in human spermatozoa and its prognostic value in in vitro fertilization: a preliminary study

M Benchaib, M Ajina, J Lornage, A Niveleau… - Fertility and …, 2003 - Elsevier
Sperm DNA methylation level and HI are correlated with sperm DNA characteristics. HI is
negatively correlated with fertilization rate; sperm DNA methylation level is correlated with …

[HTML][HTML] Obesity-related DNA methylation at imprinted genes in human sperm: results from the TIEGER study

A Soubry, L Guo, Z Huang, C Hoyo, S Romanus… - Clinical …, 2016 - Springer
… Linear regression models were used to compare sperm DNA methylation percentages,
quantified by bisulfite pyrosequencing, at 12 differentially methylated regions (DMRs) from 23 …

Oxidative DNA damage impairs global sperm DNA methylation in infertile men

O Tunc, K Tremellen - Journal of assisted reproduction and genetics, 2009 - Springer
Methylation of sperm DNA is impaired in many infertile men … damage to DNA and
hyperhomocysteinaemia are linked with DNA … if these pathologies also impair sperm DNA