Intragenic DNA methylation: implications of this epigenetic mechanism for cancer research
N Shenker, JM Flanagan - British journal of cancer, 2012 - nature.com
… Epigenetics is the study of all mechanisms that regulate gene transcription and genome …
the DNA sequence itself. The best-studied epigenetic mechanism to date is DNA methylation, …
the DNA sequence itself. The best-studied epigenetic mechanism to date is DNA methylation, …
Epigenetic mechanisms in mammals
JK Kim, M Samaranayake, S Pradhan - Cellular and molecular life …, 2009 - Springer
… Interestingly, in the same study, CGIs displayed tissue-specific methylation of genes …
mechanism of DNA methylation. Another means of DNA methylation propagation is via methylation …
mechanism of DNA methylation. Another means of DNA methylation propagation is via methylation …
DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms
… epigenetic modification, namely methylation of the Lcyc gene, rather than by a conventional
mutation, and this epigenetic … argue that this type of epigenetic alteration, while uncommon …
mutation, and this epigenetic … argue that this type of epigenetic alteration, while uncommon …
[HTML][HTML] Elevation in S-adenosylhomocysteine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology
SJ James, S Melnyk, M Pogribna, IP Pogribny… - The Journal of …, 2002 - Elsevier
… , are important metabolic indicators of cellular methylation status. Chronic elevation in …
inhibition of DNA methyltransferases. SAH-mediated DNA hypomethylation and associated …
inhibition of DNA methyltransferases. SAH-mediated DNA hypomethylation and associated …
[HTML][HTML] Genetics, epigenetic mechanism
… DNA methylation is an epigenetic mechanism associated with gene silencing when the
methylation … These epigenetic modifications can be induced by several factors including age, diet…
methylation … These epigenetic modifications can be induced by several factors including age, diet…
DNA methylation, an epigenetic mechanism connecting folate to healthy embryonic development and aging
… established through epigenetic reprogramming. However, established DNA methylation
patterns … on early development and aging through an epigenetic mechanism, DNA methylation. …
patterns … on early development and aging through an epigenetic mechanism, DNA methylation. …
Epigenetic mechanisms in the context of complex diseases
J Van Vliet, NA Oates, E Whitelaw - Cellular and molecular life sciences, 2007 - Springer
… the methylation of DNA, the post-translational modifications of histone proteins, and RNA-based
silencing. Epigenetics … Although our understanding of the role played by epigenetics in …
silencing. Epigenetics … Although our understanding of the role played by epigenetics in …
Epigenetic mechanism in regulation of endothelial function by disturbed flow: induction of DNA hypermethylation by DNMT1
… evidence that epigenetic mechanisms such as changes in DNA methylation and histone …
of the risk factors for atherogenesis, on DNA methylation in HUVECs and rat carotid arteries. …
of the risk factors for atherogenesis, on DNA methylation in HUVECs and rat carotid arteries. …
Mammalian epigenetic mechanisms
G Zhang, S Pradhan - IUBMB life, 2014 - Wiley Online Library
… DNA methylation is the most commonly studied epigenetic … methylated DNA have been
shown to be a major mechanism of … regulatory mechanism by appropriate gene methylation is of …
shown to be a major mechanism of … regulatory mechanism by appropriate gene methylation is of …
DNA hypomethylation in the origin and pathogenesis of human diseases
IP Pogribny, FA Beland - Cellular and Molecular Life Sciences, 2009 - Springer
… The recognition of the role of epigenetic mechanisms in carcinogenesis and results of …
not only by genetic but also by epigenetic mechanisms [157] have challenged our current …
not only by genetic but also by epigenetic mechanisms [157] have challenged our current …
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