Prenatal programming in an obese swine model: sex-related effects of maternal energy restriction on morphology, metabolism and hypothalamic gene expression

C Ovilo, A González-Bulnes, R Benitez… - British Journal of …, 2014 - cambridge.org
… in an obese pig model and to define the potential role of hypothalamic gene expression in
… metabolic status, and hypothalamic expression of genes implicated in energy homeostasis, …

Identification of genes regulating growth and fatness traits in pig through hypothalamic transcriptome analysis

D Pérez-Montarelo, O Madsen, E Alves… - Physiological …, 2014 - journals.physiology.org
pig constitutes a widely studied animal model for human … the hypothalamus in the regulation
of growth, fat accumulation, … relevance of the hypothalamic LEPR gene expression in growth …

Expression studies of six human obesity‐related genes in seven tissues from divergent pig breeds

S Cirera, MS Jensen, VS Elbrønd… - Animal …, 2014 - Wiley Online Library
… The pig has emerged as a very promising biomedical model … on the expression in adipose
tissues and hypothalamus. Thus, … view on FTO expression in both lean and obese individuals. …

Gene expression in hypothalamus, liver, and adipose tissues and food intake response to melanocortin-4 receptor agonist in pigs expressing melanocortin-4 receptor …

CR Barb, GJ Hausman, R Rekaya… - Physiological …, 2010 - journals.physiology.org
… have been identified in the hypothalamus of the pig (19, 44), … In this study, the following
mixed linear model was used to … , differentially expressed genes in hypothalamic, liver, and fat

[HTML][HTML] Expression of selenoprotein genes is affected by obesity of pigs fed a high-fat diet

H Zhao, K Li, JY Tang, JC Zhou, KN Wang, XJ Xia… - The Journal of …, 2015 - Elsevier
… , adipocytokines, and obesity-related gene expressions in the … in thyroid, pancreas, liver,
and hypothalamus. All these organs … The pig model used in this study would be ideal for such …

Hypothalamic expression of porcine leptin receptor (LEPR), neuropeptide Y (NPY), and cocaine-and amphetamine-regulated transcript (CART) genes is influenced by …

C Ovilo, A Fernández, AI Fernández, JM Folch… - Mammalian …, 2010 - Springer
fat thickness, and hypothalamic LEPR gene expression in both populations. Allele T fixed in
the Iberian breed is systematically associated with a higher growth and fat … linear model with …

Prenatal programming in an obese swine model Sex-related effects of maternal energy restriction on morphology, metabolism and hypothalamic gene expression

C Óvilo Martín, A González De Bulnes… - sidalc.net
… in an obese pig model and to define the potential role of hypothalamic gene expression in
… metabolic status, and hypothalamic expression of genes implicated in energy homeostasis, …

Pigs fed saturated fat/cholesterol have a blunted hypothalamic-pituitary-adrenal function, are insulin resistant and have decreased expression of IRS-1, PGC1α and …

MA Lomax, G Karamanlidis, J Laws… - The Journal of …, 2013 - Elsevier
… growing porcine model to … expression levels of IR and IRS-1 mRNA in porcine tissues. HSFC
feeding decreased both IR and IRS-1 mRNA expression in muscle and IRS-1 expression in …

Prenatal programming of obesity in a swine model of leptin resistance: modulatory effects of controlled postnatal nutrition and exercise

A Barbero, S Astiz, C Ovilo, CJ Lopez-Bote… - … Origins of Health and …, 2014 - cambridge.org
… Prenatal programming in an obese swine model: sex-related effects of maternal caloric
restriction on morphology, metabolism and hypothalamic gene expression. Br J Nutr. 2014; 111, …

Unraveling molecular mechanisms involved in the development of leptin resistance using the pig as a model

E Mármol‐Sánchez, JS Artman, M Fredholm… - Animal …, 2021 - Wiley Online Library
… according to mesenteric fat content and LEP gene expression in MESf … expression profiles
of 94 genes in CNS (cortex, cerebellum and hypothalamus) and MESf, as well as of six genes