… in infertile men. Loss of methylation was detected in the paternally imprinted and methylated
DMRs of H19 and … The human IGF2–H19 locus contains three DMRs: the IGF2 DMR0, the …

… infertile men with low sperm counts display hypermethylation of the MEST DMR and
hypomethylation of the IGF2/H19 … of well-characterized idiopathic infertile men compared with a …

… in the H19 gene in infertile male patients and a 9.91-fold higher risk of DMR aberration in the
H19 … infertility showed that impaired H19/IGF2 methylation, characterized by an increased …

… cause male infertility, we further analyzed the DNA methylation rates of H19 DMR, IGF2 …
sperm samples from male patients with normal semen (for IVF) and male patients with OAZ (…

… We recently reviewed the epigenetics of male fertility, mainly … infertile patients compared
to controls, and the most investigated pair of differentially methylated genes is H19/IGF2 …

… analysis to exclude male factor. This diagnosis points to a factor resulting in infertility that
cannot be … Patients were selected from couples with one year's infertility and normal baseline …

… of lncRNA H19 on both female and male infertility, summarizes the role of H19 in infertility,
and … (ICR) for the IGF2 and H19 genes is situated 2.5 kb upstream of the H19 promoter region. …

… H19 is physically and functionally linked to the IGF2 (insulin-like growth factor 2) gene,
being reciprocally expressed in endoderm and mesoderm tissues during the foetal life and …

… gene refers to the ICR of the locus, and its deletion impacts both H19 and IGF2 expression.
In addition, the small sample sizes used in the study may lead to lower statistical significance …

… Results showed significant correlation between ROS levels and H19-Igf2 gene methylation
as well as semen parameters. These findings are critical to identify idiopathic male infertility …