… Here, we demonstrate that male infertility is associated to H19 reduced sperm … for IGF2 and
maternal for H19). Only one trial suggested the relationship between IGF2 and male infertility, …

… (ART) have helped numerous previously infertile couples to conceive and bear children. Nearly
… F1 hybrid embyros were created by mating a male Mus. spretus with a female C57BL/6J. …

… To date, epimutations at paternal loci have been observed in the spermatozoa of infertile
men… Methylation studies revealed hypomethylation of the paternally derived H19/IGF2 locus. As …

… that arose from copulation of male and female mice were … of H19/Igf2 DMD was analyzed
by cloning and sequencing following DNA bisulfite treatment. The expression of H19 and Igf2 …

… Here, we investigated the association of methylation status of imprinted genes (H19, INS-IGF2,
KCNQ1, MEG3, MEST, PEG3 and SNRPN) with sperm DNA damage in infertile men. …

… To investigate H19 and Igf2 imprinting on the paternal allele, we bred male … were obtained
from the University of Pennsylvania Fertility Clinic following routine semen analysis. As all …

… This defect could be attributed to the underlying infertility of the parents and/or the ART
process itself. The sperm of infertile men have been previously reported by our group and others …

… the percentage of methylated CpGs of H19 DMR in the F1 and F3 male offspring, respectively.
The association between male infertility and hypomethylation of H19 DMR has been well …

… Specific epigenetic alterations of IGF2-H19 locus in spermatozoa from infertile men. Eur J
Hum Genet 2010; 18:73 - 80; http://dx.doi.org/10.1038/ejhg.2009.117; PMID: 19584898 …

… of male rats to BPA leads to altered expressions of Igf2 and H19 in resorbed embryo and
hypomethylation of Igf2–H19 … at Igf2–H19 ICR in spermatozoa from infertile subjects, mainly …