… in reproduction and fertility, including … ) H19, which belongs to a highly conserved imprinted
gene cluster that also contains the reciprocally imprinted gene for insulin growth factor 2 (Igf2…

… that H19 CBS6 hypermethylation is related to the LOI of IGF2 which usually leads to an
overexpression of IGF2… Therefore, H19 CBS6 methylation potentially represents a novel clinically …

… , we analyzed the methylation status of Igf2-H19 DMR in spermatozoa of both the groups by
… on the male germ line suggesting that human obesity induced subfertility/infertility could be …

… paternally imprinted gene H19 in fertile and infertile men [16]. A … methylated region of
H19 for infertile men. In contrast, no … of aberrant methylation in infertile men has likely been …

… then prevents the H19/IGF2 common enhancers from activating the IGF2 promoter. … male
infertility treatment, with H19 hypomethylation leading to the presence of two inactive IGF2 …

… They found that hepatic Igf2 expression of the TCDD male … of Igf2/H19 methylation levels
in F3 generation. It is not entirely clear whether the mRNA or protein expression of Igf2 and H19 …

… the H19/IGF2 ICR1 methylation loss and measured a 50% reduction in total H19/IGF2 ICR1
… No previous history of infertility or genetic disease was reported in the proband's family. …

… H19), novel imprinted gene (FAM50B) and nonimprinted genes (LINE-1 and P16) DMRs in
the spermatozoa of infertile men … between low sperm motility infertile men and the aberrant …

… Although we were not yet able to identify UTY gene mutations in infertile men associated …
only by an erroneous expression of H19 but also of IGF2, which might probably affect embryo …

… have mostly concentrated on imprinted genes like H19, IGF2, MEST, PEG3, LIT1, SNRPN
and KCNQ1 in addition to some non-imprinted genes, like MTHFR and DAZL. These studies …