… This study demonstrated that hypomethylation of H19-ICR … between male infertility and
methylation status of H19-ICR and … of H19-ICR and SNRPN-ICR on the risk of male infertility. To …

… IGF2 and H19, BORIS favored methylation specific activation of IGF2 and repression of H19,
… The degree of these effects strongly correlated with a common C/T polymorphisn at the IGF2 …

… H19 was increased in the IVF/ICSI group, while that of IGF2 … side, rinsed in cold, sterile PBS
to remove blood and stored in … of male subfertile patients applying for ICSI, an intrinsic male …

… modality for treatment of male infertility in azoospermic patients and … , expressions of Igf2
and H19 mRNA targets significantly … at Igf2-H19 genomic cluster) and Imp1 (an inhibitor of Igf2 …

… in the abundance of IGF2 receptors and downstream signalling … control expression levels
of Igf2 and H19, the placental Lz … that regulation of the Igf2/H19 locus modulates placental …

… methylation level had significant impact on male fertility and embryonic development [21]. …
H19 was related to spontaneous abortion [6]. It was reported that the expression level of H19 …

… between male infertility and … of male infertility. Therefore, molecular biologists are increasingly
trying to study whether sperm epigenetic alterations may be involved in male infertility and …

… Worryingly, PCOS is a common cause of female infertility, accounting for 75% of cases …
H19 is subject to genomic imprinting, along with the IGF2 gene, which is located adjacent to H19 …

… genes LIT1, MEST, PLAGL1, PEG3, H19, and IGF2) and found that infertile males displayed
increased methylation in these genes (with the exception of IGF2). Botezatu et al. also …

… , Igf2 is biallelically transcribed in the CNS. In this study, we examined the allelic DNA
methylation and CTCF binding in the Igf2/H19 … leads to biallelic expression of Igf2 in CNS. Using …