[HTML][HTML] DNA methylation and immune memory response

NN Mittelstaedt, AL Becker, DN de Freitas, RF Zanin… - Cells, 2021 - mdpi.com
… Here, we focus on DNA methylation and its role on memory CD4 T cells. Memory CD4 T cells
are classified as central cells (TCM) and effector cells (TEM), according to their capability to …

[HTML][HTML] DNA methylation sustains “inflamed” memory of peripheral immune cells aggravating kidney inflammatory response in chronic kidney disease

XJ Chen, H Zhang, F Yang, Y Liu, G Chen - Frontiers in Physiology, 2021 - frontiersin.org
response in the recruited effector cells. We and others recently demonstrated that altered
DNA methylation occurs in peripheral immuneDNA methylation on circulating immune cells …

DNA methylation as a transcriptional regulator of the immune system

L Morales-Nebreda, FS McLafferty, BD Singer - Translational Research, 2019 - Elsevier
… providing a long-lasting memory to fight recurrent triggers (immunologic memory) and at the
… divide the immune response into innate and adaptive immunity. Innate immunity exhibits …

[HTML][HTML] Comparative analysis of the DNA methylation landscape in CD4, CD8, and B memory lineages

Z Zhang, R Butler, DC Koestler, S Bell-Glenn… - Clinical …, 2022 - Springer
… at the DNA level for immune memory generation. Further, in central to effector memory
Further, the AIM2 locus is critical for generating B cell immune memory [39], and we find …

[HTML][HTML] The role of host cell DNA methylation in the immune response to bacterial infection

W Qin, BP Scicluna, T van der Poll - Frontiers in immunology, 2021 - frontiersin.org
… host immunity to eliminate pathogens or benefit pathogens to evade immune responses for
… of DNA methylation on host immune responses and pathogen elimination during infection. …

Adaptation and memory in immune responses

G Natoli, R Ostuni - Nature immunology, 2019 - nature.com
Immunological memory is defined as the ability of immune cells to specifically ‘remember’
the first encounter with a given antigen and to mount a secondary responseDNA methylation

[HTML][HTML] Insights into the role of DNA methylation in immune cell development and autoimmune disease

J Li, L Li, Y Wang, G Huang, X Li, Z Xie… - Frontiers in Cell and …, 2021 - frontiersin.org
… function and distribution of DNA methylation, evaluate its … In addition, we summarize
recent aberrant DNA methylation … key mediators in immunity and immunologic memory. Their …

DNA methylation: a promising landscape for immune system-related diseases

B Suarez-Alvarez, RM Rodriguez, MF Fraga… - Trends in Genetics, 2012 - cell.com
DNA methylation patterns are modified during hematopoietic differentiation and what their
role is in cell plasticity and immune … We focus here on DNA methylation, which is essential for …

[HTML][HTML] Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes

L Tserel, R Kolde, M Limbach, K Tretyakov, S Kasela… - Scientific reports, 2015 - nature.com
… We studied age-related changes in DNA methylation and gene … , with increased number
of methylation changes and higher … inverse correlation between methylation and expression …

[HTML][HTML] The immune factors driving DNA methylation variation in human blood

J Bergstedt, SAK Azzou, K Tsuo, A Jaquaniello… - Nature …, 2022 - nature.com
… We show that DNA methylation differs substantially between naïve and memory T cells, …
By doing so, we find that latent cytomegalovirus infection drives DNA methylation variation …