DNA methylation in regulatory T cell differentiation and function: challenges and opportunities

L Bai, X Hao, J Keith, Y Feng - Biomolecules, 2022 - mdpi.com
DNA methylation involved in Treg cell development, lineage stability and plasticity, as well
as immune … further investigating the immunological roles and underlying mechanisms of DNA

DNA methylation and demethylation in plant immunity

A Deleris, T Halter, L Navarro - Annual review of phytopathology, 2016 - annualreviews.org
… and co-transcriptional control of immune-responsive genes. … of DNA methylation changes
during plant immune responses and … , DNA methylation and demethylation in systemic immune

Bacterial infection remodels the DNA methylation landscape of human dendritic cells

A Pacis, L Tailleux, AM Morin, J Lambourne… - Genome …, 2015 - genome.cshlp.org
immunity, our results raise the possibility that changes in DNA methylation might also contribute
to short-term memory in … Innate immune memory: towards a better understanding of host …

T‐cell memory differentiation: insights from transcriptional signatures and epigenetics

B Youngblood, JS Hale, R Ahmed - Immunology, 2013 - Wiley Online Library
… cell division of memory cells.18, 19 Recently several laboratories have demonstrated that
epigenetic modifications, namely histone modifications and DNA methylation, modulate …

Reshaping the tumour immune microenvironment in solid tumours via tumour cell and immune cell DNA methylation: from mechanisms to therapeutics

F Zhong, Y Lin, L Zhao, C Yang, Y Ye… - British Journal of Cancer, 2023 - nature.com
… mechanisms by which DNA methylation participates in carcinogenesis, and illustrate how
DNA methylation and demethylation impact the differentiation of immune cells. Considering …

[HTML][HTML] Lymphocyte DNA methylation mediates genetic risk at shared immune-mediated disease loci

AD Clark, N Nair, AE Anderson… - Journal of allergy and …, 2020 - Elsevier
… evidence that disease-associated DNA variants regulate cis-CpG methylation in CD4 + T …
, we identify examples where site-specific DNA methylation in turn mediates gene expression, …

Altered immune phenotype and DNA methylation in panic disorder

CL Petersen, JQ Chen, LA Salas, BC Christensen - Clinical epigenetics, 2020 - Springer
… Additionally, alterations in the methylation of repetitive DNA elements, such as LINE-1, have
… peripheral blood DNA methylation data from two studies and an updated DNA methylation

DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion

C Chappell, C Beard, J Altman, R Jaenisch… - The Journal of …, 2006 - journals.aai.org
… lacking DNA methyltransferases has thwarted the ability to study DNA methylation during …
requirement of maintaining DNA methylation patterns for proper effector and memory CD8 + T …

DNA methylation-derived immune cell profiles and risk of cancers in Black participants in the ARIC Study

CS Semancik, N Zhao, D Koestler, E Boerwinkle… - Cancer Research, 2024 - AACR
… Methods: In this study, DNA methylation was measured in blood samples … Immune cell
subtype proportions were estimated using deconvolution based on leukocyte DNA methylation

Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression

E Ewing, L Kular, SJ Fernandes, N Karathanasis… - …, 2019 - thelancet.com
… investigated DNA methylation changes in both RRMS and SPMS stages and in four immune
… We observed evidence of shared DNA methylation changes across all cell types and we …