[HTML][HTML] Increased DNA methylation variability in type 1 diabetes across three immune effector cell types
DS Paul, AE Teschendorff, MAN Dang, R Lowe… - Nature …, 2016 - nature.com
… The contribution of such DNA methylation outliers in non-cancerous tissues … DNA methylation
in 52 MZ twin pairs discordant for T1D. In these twin pairs, we perform an EWAS in immune …
in 52 MZ twin pairs discordant for T1D. In these twin pairs, we perform an EWAS in immune …
[HTML][HTML] The interaction between DNA methylation and tumor immune microenvironment: from the laboratory to clinical applications
D Zhu, S Zeng, C Su, J Li, Y Xuan, Y Lin, E Xu… - Clinical Epigenetics, 2024 - Springer
… underlying DNA methylation in the … , DNA methylation of both tumor cells and immune cells
interacts with the TIME, and thus affects clinical efficacy. The regulation of DNA methylation …
interacts with the TIME, and thus affects clinical efficacy. The regulation of DNA methylation …
Whole-genome profiling of DNA methylation and hydroxymethylation identifies distinct regulatory programs among innate lymphocytes
… Removal of DNA methylation can be conducted via several biochemical pathways. First, a …
DNA methylation during replication can lead to passive and gradual loss of DNA methylation …
DNA methylation during replication can lead to passive and gradual loss of DNA methylation …
[HTML][HTML] Role of DNA methylation in the regulation of cell function: autoimmunity, aging and cancer
BC Richardson - The Journal of nutrition, 2002 - Elsevier
… DNA methylation plays an essential role in maintaining cellular function, and changes in
methylation … that inhibiting T lymphocyte DNA methylation causes autoreactivity in vitro and a …
methylation … that inhibiting T lymphocyte DNA methylation causes autoreactivity in vitro and a …
[HTML][HTML] DNA methylation in whole blood: uses and challenges
EA Houseman, S Kim, KT Kelsey… - Current environmental …, 2015 - Springer
… component of the immune response to the … DNA methylation in the blood, highlighting cell
composition effects through evidence of involvement in the immune or inflammatory responses …
composition effects through evidence of involvement in the immune or inflammatory responses …
[HTML][HTML] DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4+ T-Cell Population Structure
… changes reflect changes in DNA methylation in a given type … explain the difference in DNA
methylation profile we observed … potential to stratify immune diseases with DNA methylation. …
methylation profile we observed … potential to stratify immune diseases with DNA methylation. …
Short-term memory of danger signals and environmental stimuli in immune cells
S Monticelli, G Natoli - Nature immunology, 2013 - nature.com
… Standard definitions of immunological memory are all built … the response of cells of both the
innate and adaptive immune … At the other end of the spectrum is DNA methylation, which is …
innate and adaptive immune … At the other end of the spectrum is DNA methylation, which is …
Induction of innate immune memory: the role of cellular metabolism
J Domínguez-Andrés, LAB Joosten… - Current opinion in …, 2019 - Elsevier
… immunity can develop immunological memory has recently been challenged by studies showing
that cells from the innate immune … faster and enhanced response to secondary infections…
that cells from the innate immune … faster and enhanced response to secondary infections…
[HTML][HTML] … DNA methylation of potassium channel KCa3. 1 and immune signalling pathways is associated with infant immune responses following BCG vaccination
M Hasso-Agopsowicz, TJ Scriba, WA Hanekom… - Scientific reports, 2018 - nature.com
… DNA methylation is one of the molecular mechanisms driving variability in BCG-induced
immune responses… We have examined whether the DNA methylation profile of peripheral blood …
immune responses… We have examined whether the DNA methylation profile of peripheral blood …
[HTML][HTML] Assessment of DNA methylation in porcine immune cells reveals novel regulatory elements associated with cell-specific gene expression and immune …
RJ Corbett, AM Luttman, J Herrera-Uribe, H Liu… - BMC genomics, 2022 - Springer
… Our DNA methylation data improve functional annotation of the porcine genome through
characterization of epigenomic regulatory patterns that contribute to immune cell identity and …
characterization of epigenomic regulatory patterns that contribute to immune cell identity and …