Immunological detection of changes in genomic DNA methylation during early zebrafish development

AB MacKay, AA Mhanni, RA McGowan, PH Krone - Genome, 2007 - cdnsciencepub.com
… both organisms for which DNA methylation was previously not thought … DNA methylation
occur during early zebrafish development. Although zebrafish sperm DNA is strongly methylated

DNA methylation–based immune response signature improves patient diagnosis in multiple cancers

J Jeschke, M Bizet, C Desmedt… - The Journal of …, 2017 - Am Soc Clin Investig
… TILs, with the overall aim of establishing an “immunological grade” for clinical practice (14). …
DNA methylation plays a critical role in cell lineage specification and may therefore serve as …

Metabolic, hormonal and immunological associations with global DNA methylation among postmenopausal women

C Ulrich, A Toriola, L Koepl, T Sandifer, E Poole… - Epigenetics, 2012 - Taylor & Francis
… of global DNa methylation, including biomarkers. here, we investigated associations between
DNa methylation and … Global DNa methylation in lymphocyte DNa was measured using the …

DNA methylation and autoimmune disease

B Richardson - Clinical Immunology, 2003 - Elsevier
… Abnormal DNA methylation has also been implicated in … DNA methylation inhibitors on
T-cell function and gene expression, the evidence supporting a role for altered DNA methylation

Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling

LA Salas, Z Zhang, DC Koestler, RA Butler… - Nature …, 2022 - nature.com
… based deconvolution of blood DNA methylation to include 12 … for deconvolution of DNA
methylation data for current and … mixtures and whole-blood DNA methylation with known cellular …

DNA methylation based biomarkers: practical considerations and applications

AH Kit, HM Nielsen, J Tost - Biochimie, 2012 - Elsevier
… In some cases, DNA methylation based biomarkers have proven … DNA methylation as a
biomarker, the practical considerations for their development, and their use in disease detection, …

A multiplex blood-based assay targeting DNA methylation in PBMCs enables early detection of breast cancer

T Wang, P Li, Q Qi, S Zhang, Y Xie, J Wang… - Nature …, 2023 - nature.com
DNA methylation is involved in the body’s immune response to tumors. In this work, we
investigate whether DNA methylation … be used as markers for early detection of breast cancer (BC…

DNA methylation is a nonredundant repressor of the Th2 effector program

KW Makar, CB Wilson - The Journal of Immunology, 2004 - journals.aai.org
DNA methylation has also been implicated in the regulation … 10), suggesting that DNA
methylation may help to establish and… contribution of DNA methylation and DNA methyltransferase …

Immunological methods for detection of carcinogen-DNA damage in humans

RM Santella - Cancer Epidemiology Biomarkers & Prevention, 1999 - AACR
… Competitive ELISA is the most commonly used immunological method for quantification
of DNA damage. There are numerous variations of the ELISA using alkaline phosphatase or …

Anti-mycobacterial activity correlates with altered DNA methylation pattern in immune cells from BCG-vaccinated subjects

D Verma, VR Parasa, J Raffetseder, M Martis… - Scientific reports, 2017 - nature.com
… and performed global DNA methylation analysis in combination … A stable and robust differential
DNA methylation pattern in … promoters with altered DNA methylation pattern were strongly …