The DNA methylation profile of activated human natural killer cells

JK Wiencke, R Butler, G Hsuang, M Eliot, S Kim… - Epigenetics, 2016 - Taylor & Francis
… of immunologic memory that shares many features with CD8 T effector and memory cells
following antigen activation.Citation 22 The work herein studied the DNA methylation profiles of …

Toward clinical application of leukocyte counts based on targeted DNA methylation analysis

S Sontag, L Bocova, WHG Hubens… - Clinical …, 2022 - academic.oup.com
DNA methylation (DNAm) is a covalent modification of cytosine residues, mostly at CG
dinucleotides (CpG sites) (10). By measuring the methylation level at CpG sites with cell-type–…

[HTML][HTML] DNA methylation: a timeline of methods and applications

A Harrison, A Parle-McDermott - Frontiers in genetics, 2011 - frontiersin.org
… wide DNA methylation patterns is still evolving. We review the development of DNA methylation
… prior to microarray hybridization, immunological separation techniques became relevant …

DNA methylation modulates HRES1/p28 expression in B cells from patients with Lupus

T Fali, C Le Dantec, Y Thabet, S Jousse, C Hanrotel… - …, 2014 - Taylor & Francis
… their DNA upon antigen stimulation, the aim of this study was to investigate whether DNA
-IL-6 receptor monoclonal antibody restores DNA methylation and control of HRES-1/p28 …

Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia

…, with the MRSA Systems Immunology … - Proceedings of the …, 2021 - National Acad Sciences
… emphasize how unique DNA methylation patterns may … infections are known to modify
DNA methylation in host cells (15… our hypothesis that distinct DNA methylation signatures are …

[HTML][HTML] Methotrexate treatment of newly diagnosed RA patients is associated with DNA methylation differences at genes relevant for disease pathogenesis and …

K Guderud, LH Sunde, ST Flåm, MT Mæhlen… - … in immunology, 2021 - frontiersin.org
… We detected CpG sites with DNA methylation levels associated with MTX treatment in CD4
+ naïve and memory T cells isolated from RA patients. Several of these CpGs were annotated …

DNA methylation trajectories during innate and adaptive immune responses of human B lymphocytes

KF Jhuang, ML Hsu, YC Chen, JG Chang… - …, 2023 - Wiley Online Library
… Since DNA methylation plays a key role in controlling gene … gain and loss of DNA methylation.
The epigenetic changes map … Non-CpG methylation also occurs in differentiating human B …

[HTML][HTML] DNA Methylation of T lymphocytes as a therapeutic target: Implications for rheumatoid arthritis etiology

J Zhao, K Wei, C Chang, L Xu, P Jiang, S Guo… - … in Immunology, 2022 - frontiersin.org
… Figure 1 Genetics, environment, and DNA methylation are interrelated in T cell function for
DNA methylation, histone modifications, and microRNAs. We focus on the DNA methylation

Mini-review of DNA Methylation Detection Techniques and Their Potential Applications in Disease Diagnosis, Prognosis, and Treatment

H Zhang, L Liu, M Li - ACS sensors, 2024 - ACS Publications
… in DNA methylation are closely associated with the potential onset of various diseases.
Consequently, numerous DNA methylation detection … employed DNA methylation detection

MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1

W Pan, S Zhu, M Yuan, H Cui, L Wang… - … of immunology, 2010 - journals.aai.org
… regulate DNA methylation by targeting the DNA methylation … of global DNA methylation
and the re-expression of DNA … between miRNAs and methylation regulation provides an …