Cell type–specific DNA methylation at intragenic CpG islands in the immune system
… environment regardless of methylation state. Our results indicate that DNA methylation changes
play … The dinucleotide sequence CpG is the predominant site of DNA methylation in the …
play … The dinucleotide sequence CpG is the predominant site of DNA methylation in the …
[HTML][HTML] LAG3 (LAG-3, CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell …
… DNA methylation at single CpG site resolution within the LAG3 gene. We correlated LAG3
methylation … LAG3 variants that display different effects on immunological microenvironments …
methylation … LAG3 variants that display different effects on immunological microenvironments …
Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
M Delacher, CD Imbusch, D Weichenhan… - … immunology, 2017 - nature.com
… Our analysis of the pattern of DNA methylation (the 'methylome') revealed 11,000
differentially methylated regions (DMRs) associated with about 4,000 genes. Shared epigenetic …
differentially methylated regions (DMRs) associated with about 4,000 genes. Shared epigenetic …
DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4+ T cells in response to SIV infections
… in more than one tissue or timepoint; and/or were also differentially expressed following
infection; and/or possess a known important immunological or metabolic function. These …
infection; and/or possess a known important immunological or metabolic function. These …
Immunological detection of O6-methylguanine in alkylated DNA
WT Briscoe, J Spizizen, EM Tan - Biochemistry, 1978 - ACS Publications
… react with any type of methylated base is a difficult one. To beginto answer this, DNA methylated
by an 06-methylguanine-producing carcinogen (MNU) and DNA methylated by a non-06…
by an 06-methylguanine-producing carcinogen (MNU) and DNA methylated by a non-06…
[HTML][HTML] Development and validation of a DNA methylation-related classifier of circulating tumour cells to predict prognosis and to provide a therapeutic strategy in …
X Gu, X Huang, X Zhang, C Wang - International Journal of …, 2022 - ncbi.nlm.nih.gov
… We studied DNA methylation markers in CTCs for the first time and connected them to
patient prognoses, immunological modulation, and treatment effectiveness in LUAD for the first …
patient prognoses, immunological modulation, and treatment effectiveness in LUAD for the first …
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease
… of samples and a two DNA methylation probe biomarker was found … DNA methylation,
genomic and gene expression data and to relate changes seen in whole blood to the methylation …
genomic and gene expression data and to relate changes seen in whole blood to the methylation …
Dynamic CpG-DNA methylation of Il10 and Il19 in CD4+ T lymphocytes and macrophages: effects on tissue-specific gene expression
SR Hofmann, J Möller, T Rauen, D Paul… - Klinische …, 2012 - thieme-connect.com
… DNA demethylation with 5-… CpG-DNA methylation through DNMT3a resulted in transcriptional
silencing in macrophages. Thus, our findings suggest a role of CpG-DNA methylation in …
silencing in macrophages. Thus, our findings suggest a role of CpG-DNA methylation in …
Discovery of molecular DNA methylation-based biomarkers through genome-wide analysis of response patterns to BCG for bladder cancer
D Ilijazi, W Pulverer, IE Ertl, U Lemberger, S Kimura… - Cells, 2020 - mdpi.com
… Our aim was to discover DNA methylation profiles that … DNA methylation are present in
genes related to bacterial invasion or focal adhesion. We also identify candidate DNA methylation …
genes related to bacterial invasion or focal adhesion. We also identify candidate DNA methylation …
The interaction between DNA methylation and tumor immune microenvironment: from the laboratory to clinical applications
D Zhu, S Zeng, C Su, J Li, Y Xuan, Y Lin, E Xu… - Clinical Epigenetics, 2024 - Springer
… underlying DNA methylation in the … , DNA methylation of both tumor cells and immune cells
interacts with the TIME, and thus affects clinical efficacy. The regulation of DNA methylation …
interacts with the TIME, and thus affects clinical efficacy. The regulation of DNA methylation …