Development and maturation of the immune system in zebrafish, Danio rerio: a gene expression profiling, in situ hybridization and immunological study

SH Lam, HL Chua, Z Gong, TJ Lam, YM Sin - Developmental & …, 2004 - Elsevier
… , and the detection of Ig and the onset of humoral immunity, and enable a better understanding
of the different maturation state of the immune system during zebrafish development. …

Immunological detection of changes in genomic DNA methylation during early zebrafish development

AB MacKay, AA Mhanni, RA McGowan, PH Krone - Genome, 2007 - cdnsciencepub.com
… changes during early zebrafish development reported in this study further establishes a
conserved pattern of DNA methylation in vertebrate development. Indeed, zebrafish are finding …

Immunology and zebrafish: spawning new models of human disease

ND Meeker, NS Trede - Developmental & Comparative Immunology, 2008 - Elsevier
… in developmental biology, the zebrafish has now been adopted into varied fields of study
including immunology. In this review, we describe the characteristics of the zebrafish, which …

Zebrafish as a model for infectious disease and immune function

C Sullivan, CH Kim - Fish & shellfish immunology, 2008 - Elsevier
… the zebrafish to study immune responses to infection. Although many of the zebrafish pathogen
models were developed to … The results of in vivo fluorescence-based assays for detecting

Zebrafish: model for the study of inflammation and the innate immune response to infectious diseases

B Novoa, A Figueras - Current topics in innate immunity II, 2012 - Springer
… that zebrafish can offer for immunological research. … system, have been detected in zebrafish.
Polymorphisms within … The range of tools developed for labeling neutrophils in zebrafish

Zebrafish development and regeneration: new tools for biomedical research

SA Brittijn, SJ Duivesteijn, M Belmamoune… - … of Developmental …, 2009 - pure.knaw.nl
zebrafish developmental biology. We describe phenotypic screening assays being developed
… a test compound or drug to zebrafish in vivo; (ii) the subsequent detection or "readout" of a …

Studying the immune response to human viral infections using zebrafish

MF Goody, C Sullivan, CH Kim - Developmental & Comparative …, 2014 - Elsevier
… In CHIKV-infected zebrafish larvae, primers were designed to detect expression of both
genomic RNA and subgenomic mRNA for the E1 viral spike gene. Viral transcript levels were …

[HTML][HTML] The zebrafish as a model to study intestinal inflammation

S Brugman - Developmental & Comparative Immunology, 2016 - Elsevier
… Under homeostatic conditions, we detected low expression levels at 1 wpf and at adult
age (14 wpf), but increased expression at 5 wpf both in scattered granulocytic cells and in the …

[HTML][HTML] Pathogen recognition and activation of the innate immune response in zebrafish

M van der Vaart, HP Spaink, AH Meijer - Advances in hematology, 2012 - ncbi.nlm.nih.gov
detection of ROS production in zebrafish embryos [177]. DMPO is a chemical substrate that
binds to reactive oxygen, which can later be detected … been developed for zebrafish embryos, …

The zebrafish: a new model of T-cell and thymic development

DM Langenau, LI Zon - Nature Reviews Immunology, 2005 - nature.com
… the advantages of using the zebrafish as a genetic model to uncover mutations that affect
T-cell and thymic development. Finally, we summarize the use of the zebrafish as a new model …