Role for DNA methylation in genomic imprinting

E Li, C Beard, R Jaenisch - Nature, 1993 - nature.com
… 2 gene and the active maternal allele of the Igf2r gene were repressed. Our results demonstrate
that a normal level of DNA methylation is … of imprinted genes. Embryos homozygous for a …

DNA methylation in genomic imprinting, development, and disease

M Paulsen, AC Ferguson‐Smith - The Journal of pathology, 2001 - Wiley Online Library
… of imprinted genes. This review describes possible mechanisms by which DNA methylation
can regulate gene expression, using imprinted genes as examples. The molecular basis of …

Regulation of imprinted DNA methylation

R Holmes, PD Soloway - Cytogenetic and genome research, 2006 - karger.com
… regulating imprinted DNA methylation. We will focus on cis acting DNA sequences, trans -…
Approximately 70 known imprinted genes contain allelespecific DNA methylation within a …

Role of DNA methylation in imprinting disorders: an updated review

AR Elhamamsy - Journal of Assisted Reproduction and Genetics, 2017 - Springer
imprinting. This review focuses on the role of DNA methylation in imprinting process and
describes DNA … Similarly, imprinted genes evade the first cycle of epigenetic reprogramming by …

[HTML][HTML] Newborns of obese parents have altered DNA methylation patterns at imprinted genes

A Soubry, SK Murphy, F Wang, Z Huang… - International journal of …, 2015 - nature.com
… To determine the independent effects of preconceptional maternal or paternal obesity on
offspring DNA methylation at the seven DMRs of the imprinted genes studied, we controlled for …

[HTML][HTML] Obesity-related DNA methylation at imprinted genes in human sperm: results from the TIEGER study

A Soubry, L Guo, Z Huang, C Hoyo, S Romanus… - Clinical …, 2016 - Springer
… paternal obesity and altered DNA methylation in umbilical cord … and DNA methylation status
of imprinted gene regulatory … Our data further suggest a slight increase in DNA methylation

Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis

WM Brown - British Journal of Sports Medicine, 2015 - bjsm.bmj.com
… A well-studied DNA methylation-based phenomenon is genomic imprinting (ie, genotype…
DNA methylation and (2) the role of imprinted genes in skeletal muscle gene networks (ie, gene

Should I stay or should I go: protection and maintenance of DNA methylation at imprinted genes

D Messerschmidt - Epigenetics, 2012 - Taylor & Francis
… 80 different imprinted regions, involving insulator proteins and microRNAs, yet each of them
ultimately depends on differential DNA methylation at ICRs. This methylation, established at …

… -wide DNA methylation analysis of patients with imprinting disorders identifies differentially methylated regions associated with novel candidate imprinted genes

LE Docherty, FI Rezwan, RL Poole, H Jagoe… - … of medical genetics, 2014 - jmg.bmj.com
imprinted genes that were shown to be hypomethylated in the TND patient group in this study;
the green dots represent known imprinted genes … correspond to candidate imprinted loci in …

DNA methylation and imprinting: why bother?

R Jaenisch - Trends in Genetics, 1997 - cell.com
DNA methylation is crucial for mammalian development because embryos that cannot
maintain normal methylation levels die after gastrulation. I propose that DNA methylation is only …