Abnormal methylation of imprinted genes in human sperm is associated with oligozoospermia
CJ Marques, P Costa, B Vaz, F Carvalho… - MHR-Basic Science …, 2008 - academic.oup.com
… We studied the methylation patterns of H19 and MEST imprinted genes in sperm of … a sperm
count below 10 × 10 6 /ml display defective methylation of H19 and/or MEST imprinted genes…
count below 10 × 10 6 /ml display defective methylation of H19 and/or MEST imprinted genes…
[HTML][HTML] Methylation defects of imprinted genes in human testicular spermatozoa
CJ Marques, T Francisco, S Sousa, F Carvalho… - Fertility and sterility, 2010 - Elsevier
… Here we describe the first study of the methylation status of two imprinted genes, H19 and
MEST, in these sperm cells, obtained from testicular biopsies of patients with different causes …
MEST, in these sperm cells, obtained from testicular biopsies of patients with different causes …
Sperm DNA integrity status is associated with DNA methylation signatures of imprinted genes and non-imprinted genes
B Song, C Wang, Y Chen, G Li, Y Gao, F Zhu… - … and Genetics, 2021 - Springer
… cases with impaired sperm DNA integrity). We detected the methylation status of 257 CpG
sites among two imprinted genes (H19 and SNRPN) and four non-imprinted genes related to …
sites among two imprinted genes (H19 and SNRPN) and four non-imprinted genes related to …
Methylation status of imprinted genes and repetitive elements in sperm DNA from infertile males
… sperm samples from infertile and presumably fertile males. However, in contrast to imprinted
genes… ALU methylation was significantly higher in sperm samples leading to pregnancy and …
genes… ALU methylation was significantly higher in sperm samples leading to pregnancy and …
Genome-wide analysis identifies changes in histone retention and epigenetic modifications at developmental and imprinted gene loci in the sperm of infertile men
SS Hammoud, DA Nix, AO Hammoud… - Human …, 2011 - academic.oup.com
… The sperm chromatin of fertile men retains a small number of nucleosomes that are … gene
promoters and imprinted gene loci. This unique chromatin packaging at certain gene promoters …
promoters and imprinted gene loci. This unique chromatin packaging at certain gene promoters …
Obesity-related DNA methylation at imprinted genes in human sperm: results from the TIEGER study
A Soubry, L Guo, Z Huang, C Hoyo, S Romanus… - Clinical …, 2016 - Springer
… that regulate monoallelic expression of imprinted genes. In males, this … status of imprinted
gene regulatory regions in the gametes. … epigenetic studies on human (maturing) sperm in the …
gene regulatory regions in the gametes. … epigenetic studies on human (maturing) sperm in the …
Relevance of sperm imprinted gene methylation on assisted reproductive technique outcomes and pregnancy loss: a systematic review
R Cannarella, A Crafa, RA Condorelli… - Systems Biology in …, 2021 - Taylor & Francis
… Recent evidence suggests that gamete-imprinted genes play a role in embryo and placenta
… altered methylation of sperm-imprinted genes associates with sperm DNA fragmentation (…
… altered methylation of sperm-imprinted genes associates with sperm DNA fragmentation (…
[HTML][HTML] The role of imprinted genes in humans
M Ishida, GE Moore - Molecular aspects of medicine, 2013 - Elsevier
… the specific dosage of imprinted genes can lead to various … imprinted gene was discovered,
many different mechanisms have been implicated in this special regulatory mode of gene …
many different mechanisms have been implicated in this special regulatory mode of gene …
DNA methylation levels of imprinted and nonimprinted genes DMR s associated with defective human spermatozoa
J Xu, A Zhang, Z Zhang, P Wang, Y Qian, L He… - Andrologia, 2016 - Wiley Online Library
… of methylation status of familiar imprinted genes (MEST, GNAS, FAM50B and H19), and
nonimprinted genes (P16) methylation levels in the spermatozoa of infertile men with single-…
nonimprinted genes (P16) methylation levels in the spermatozoa of infertile men with single-…
What the human sperm methylome tells us
C Camprubí, RA Cigliano, A Salas-Huetos… - …, 2017 - Taylor & Francis
… Large-scale DNA methylation studies in human sperm from fertile individuals reveal that
the … and somatic differentially methylated regions (DMRs) of reported imprinted genes? …
the … and somatic differentially methylated regions (DMRs) of reported imprinted genes? …
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