Epigenetic germline mosaicism in infertile men
S Laurentino, J Beygo, V Nordhoff… - … molecular genetics, 2015 - academic.oup.com
… imprinted genes are methylated either in oocytes or in sperm… Paternally imprinted genes are
methylated in sperm (and … way, maternally imprinted genes are unmethylated in sperm and …
methylated in sperm (and … way, maternally imprinted genes are unmethylated in sperm and …
[PDF][PDF] Imprinting of mammalian male gametes is gene specific and does not occur at a single stage of differentiation.
MD Boyano, N Andollo, MM Zalduendo… - International Journal of …, 2008 - researchgate.net
… the U2af1-rs1 and H19 imprinted genes in a mouse male PGC derived cell line (EG1),
isolated spermatogonia from 6-7 day old mouse testes and mature sperm cells. Our data indicate …
isolated spermatogonia from 6-7 day old mouse testes and mature sperm cells. Our data indicate …
A screen for retrotransposed imprinted genes reveals an association between X chromosome homology and maternal germ-line methylation
Imprinted genes undergo epigenetic modifications … imprinting and the products of
retrotransposition, but the nature of this link is not well defined. In the mouse, three imprinted genes …
retrotransposition, but the nature of this link is not well defined. In the mouse, three imprinted genes …
Acquisition of theH19Methylation imprint occurs differentially on the parental alleles during spermatogenesis
TL Davis, JM Trasler, SB Moss, GJ Yang… - Genomics, 1999 - Elsevier
… in this region is inherited from sperm and retained on the … of imprinted genes in the postnatal
testis demonstrated that … acquisition of methylation at imprinted genes, we have performed a …
testis demonstrated that … acquisition of methylation at imprinted genes, we have performed a …
Epigenetics, spermatogenesis and male infertility
S Rajender, K Avery, A Agarwal - Mutation Research/Reviews in Mutation …, 2011 - Elsevier
… spermatozoa that may not have established proper imprints or global methylation. Epigenetic
changes, in contrast to genetic … Paternally imprinted genes are found in the male germ line …
changes, in contrast to genetic … Paternally imprinted genes are found in the male germ line …
Imprinting in the germ line
JR Mann - Stem Cells, 2001 - academic.oup.com
… been reported—mammalian testicular teratomas are thought to … basis, as the egg and sperm
each provides the same DNA … as far as we know, imprinted genes are a special case only in …
each provides the same DNA … as far as we know, imprinted genes are a special case only in …
Inheritance of paternal lifestyles and exposures through sperm DNA methylation
KW Greeson, KMS Crow, RC Edenfield… - Nature Reviews …, 2023 - nature.com
… blood–testis … imprinted genes, H19 DMR and IG-DMR in human sperm 83 and tobacco
smoking has being linked to increased DNA methylation levels at the DLK1 DMR in men’s sperm …
smoking has being linked to increased DNA methylation levels at the DLK1 DMR in men’s sperm …
[HTML][HTML] Identification of the mouse paternally expressed imprinted gene Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on chromosome 2
H Kobayashi, K Yamada, S Morita, H Hiura, A Fukuda… - Genomics, 2009 - Elsevier
… and sperms revealed that this region was hypomethylated in oocytes but highly methylated
in sperms. … showed biallelic expression specifically in placenta and testis, like Zdbf2 gene. By …
in sperms. … showed biallelic expression specifically in placenta and testis, like Zdbf2 gene. By …
Fertilization and embryonic developmental capacity of epididymal and testicular sperm and immature spermatids and spermatocytes
O Lacham-Kaplan, A Trounson - Reproductive Medicine Review, 1997 - cambridge.org
… expression of genetically imprinted genes that are regulatory suppressor genes may induce
… genes, causing cancers.To date 12 genes have been identified as genomically imprinted in …
… genes, causing cancers.To date 12 genes have been identified as genomically imprinted in …
[HTML][HTML] Transgenerational epigenetic programming of the embryonic testis transcriptome
MD Anway, SS Rekow, MK Skinner - Genomics, 2008 - Elsevier
… A known imprinted gene (ie, H19) was found not … male fertility [6], as well as a variety of
other disease states [6]. Investigation of the transgenerational sperm epigenome identified genes/…
other disease states [6]. Investigation of the transgenerational sperm epigenome identified genes/…