Epigenetic germline mosaicism in infertile men

S Laurentino, J Beygo, V Nordhoff… - … molecular genetics, 2015 - academic.oup.com
imprinted genes are methylated either in oocytes or in sperm… Paternally imprinted genes are
methylated in sperm (and … way, maternally imprinted genes are unmethylated in sperm and …

[PDF][PDF] Imprinting of mammalian male gametes is gene specific and does not occur at a single stage of differentiation.

MD Boyano, N Andollo, MM Zalduendo… - International Journal of …, 2008 - researchgate.net
… the U2af1-rs1 and H19 imprinted genes in a mouse male PGC derived cell line (EG1),
isolated spermatogonia from 6-7 day old mouse testes and mature sperm cells. Our data indicate …

A screen for retrotransposed imprinted genes reveals an association between X chromosome homology and maternal germ-line methylation

AJ Wood, RG Roberts, D Monk, GE Moore… - … Genetics, 2007 - journals.plos.org
Imprinted genes undergo epigenetic modifications … imprinting and the products of
retrotransposition, but the nature of this link is not well defined. In the mouse, three imprinted genes

Acquisition of theH19Methylation imprint occurs differentially on the parental alleles during spermatogenesis

TL Davis, JM Trasler, SB Moss, GJ Yang… - Genomics, 1999 - Elsevier
… in this region is inherited from sperm and retained on the … of imprinted genes in the postnatal
testis demonstrated that … acquisition of methylation at imprinted genes, we have performed a …

Epigenetics, spermatogenesis and male infertility

S Rajender, K Avery, A Agarwal - Mutation Research/Reviews in Mutation …, 2011 - Elsevier
spermatozoa that may not have established proper imprints or global methylation. Epigenetic
changes, in contrast to genetic … Paternally imprinted genes are found in the male germ line …

Imprinting in the germ line

JR Mann - Stem Cells, 2001 - academic.oup.com
… been reported—mammalian testicular teratomas are thought to … basis, as the egg and sperm
each provides the same DNA … as far as we know, imprinted genes are a special case only in …

Inheritance of paternal lifestyles and exposures through sperm DNA methylation

KW Greeson, KMS Crow, RC Edenfield… - Nature Reviews …, 2023 - nature.com
… blood–testisimprinted genes, H19 DMR and IG-DMR in human sperm 83 and tobacco
smoking has being linked to increased DNA methylation levels at the DLK1 DMR in men’s sperm

[HTML][HTML] Identification of the mouse paternally expressed imprinted gene Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on chromosome 2

H Kobayashi, K Yamada, S Morita, H Hiura, A Fukuda… - Genomics, 2009 - Elsevier
… and sperms revealed that this region was hypomethylated in oocytes but highly methylated
in sperms. … showed biallelic expression specifically in placenta and testis, like Zdbf2 gene. By …

Fertilization and embryonic developmental capacity of epididymal and testicular sperm and immature spermatids and spermatocytes

O Lacham-Kaplan, A Trounson - Reproductive Medicine Review, 1997 - cambridge.org
… expression of genetically imprinted genes that are regulatory suppressor genes may induce
genes, causing cancers.To date 12 genes have been identified as genomically imprinted in …

[HTML][HTML] Transgenerational epigenetic programming of the embryonic testis transcriptome

MD Anway, SS Rekow, MK Skinner - Genomics, 2008 - Elsevier
… A known imprinted gene (ie, H19) was found not … male fertility [6], as well as a variety of
other disease states [6]. Investigation of the transgenerational sperm epigenome identified genes/…