Obesity-related DNA methylation at imprinted genes in human sperm: results from the TIEGER study

A Soubry, L Guo, Z Huang, C Hoyo, S Romanus… - Clinical …, 2016 - Springer
… of overweight/obese men in this study could persist in their offspring. Taken together, the
results of the NEST and TIEGER studies suggest that linkages between sperm and offspring …

Exposure to organophospate contaminants is associated with aberrant DNA methylation at imprinted genes in sperm: results of the TIEGER study.

A Soubry*, CM Butt, S Fieuws, C Hoyo… - ISEE Conference …, 2016 - ehp.niehs.nih.gov
… Prior studies on animals have shown that paternal exposures to environmental conditions
alter the sperm epigenome. Growth regulating imprinted genes are reasonable targets to …

The imprinted gene and parent-of-origin effect database

IM Morison, CJ Paton, SD Cleverley - Nucleic Acids Research, 2001 - academic.oup.com
… lion–tigerimprinted gene expression can simply reflect the technical problems of allelic
drop-out during RT–PCR whentranscript frequency is rare, while some of the reported imprinted

DNA methylation of imprinted genes in Mexican–American newborn children with prenatal phthalate exposure

G Tindula, SK Murphy, C Grenier, Z Huang, K Huen… - …, 2018 - Taylor & Francis
… In this study, we have focused on nine imprinted gene DMRs that have been previously
established and validated, and we intend to explore other regions with parental-origin-…

Human exposure to flame-retardants is associated with aberrant DNA methylation at imprinted genes in sperm

A Soubry, C Hoyo, CM Butt, S Fieuws… - Environmental …, 2017 - academic.oup.com
… The distribution of BMI in our TIEGER study population is not representative of young men
in North Carolina. We corrected for BMI status and age, and we repeated our analyses in a …

Allele-specific methylation of imprinted genes in fetal cord blood is influenced by cis-acting genetic variants and parental factors

R Potabattula, M Dittrich, J Böck, L Haertle, T Müller… - …, 2018 - Taylor & Francis
… bisulphite sequencing assays for six imprinted genes to determine parental allele-… most
imprinted genes was largely dependent on the underlying SNP haplotype. Conclusion: Our study

Transgenerational effects of bisphenol A on gene expression and DNA methylation of imprinted genes in brain

Z Drobná, AD Henriksen, JT Wolstenholme… - …, 2018 - academic.oup.com
… We performed follow-up studies to verify the results of RNA-seq, and here we report on …
imprinted genes Meg3 and Mirg. Both genes produce noncoding RNAs present in the imprinted

Imprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life

M Lorgen-Ritchie, AD Murray, R Staff… - Scientific reports, 2021 - nature.com
study we hypothesize that associations exist between imprint … We report that methylation
within the imprinted genes, H19/… As with most studies of imprinting, the magnitude of methylation …

[图书][B] Genomic imprinting and kinship

D Haig - 2002 - books.google.com
… has been the willingness of some firstrate molecular biologists to learn something about …
adaptations of imprinted genes and adaptations of genes that apply the imprints (see paper …

Genomic map of candidate human imprint control regions: the imprintome

DD Jima, DA Skaar, A Planchart, A Motsinger-Reif… - Epigenetics, 2022 - Taylor & Francis
… Sperm DNA was from the TIEGER study at Duke [Citation23]. … ICRs (red boxes) determined
in this study, and potentially control novel imprinted genes. The methylation levels for ICRs is …