A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome

CJ Brown, A Ballabio, JL Rupert, RG Lafreniere… - Nature, 1991 - nature.com
… Here we describe an X-linked gene with a novel expression pattern-transcripts are detected
only from the inactive X chromosome (Xi) and not from the active X chromosome (X). This …

[HTML][HTML] Female human iPSCs retain an inactive X chromosome

J Tchieu, E Kuoy, MH Chin, H Trinh, M Patterson… - Cell stem cell, 2010 - cell.com
… II) or are clonal, with one of the two X chromosomes exclusively being inactive (Figure 4A,
I), … enzyme digest patterns between the two X chromosomes, by sequencing of relevant …

Delving into the diversity of facultative heterochromatin: the epigenetics of the inactive X chromosome

E Heard - Current opinion in genetics & development, 2005 - Elsevier
inactive X and, presumably, is also a result of its spatio-temporal segregation. The inactive
X chromosome … , the epigenetic tapestry of the inactive X is just beginning to be unravelled. …

Characterization of a murine gene expressed from the inactive X chromosome

G Borsani, R Tonlorenzi, MC Simmler, L Dandolo… - Nature, 1991 - nature.com
… Xist is the only gene known to be expressed from the murine inactive X chromosome and
the only one among those also expressed from the human inactive X chromosome to show an …

Structural organization of the inactive X chromosome in the mouse

L Giorgetti, BR Lajoie, AC Carter, M Attia, Y Zhan, J Xu… - Nature, 2016 - nature.com
… Chadwick, Deletion of the macrosatellite DXZ4 on the human inactive X chromosome alters
… (E1) where the active X is on the 129 allele and the inactive X chromosome on the Cast, and …

Structural aspects of the inactive X chromosome

G Bonora, CM Disteche - Philosophical Transactions of …, 2017 - royalsocietypublishing.org
… material that might arise from the X chromosome being … one of the two X chromosomes
exhibited the particular structure. … a manifestation of an inactivated X chromosome with respect to …

[HTML][HTML] The human inactive X chromosome modulates expression of the active X chromosome

AK San Roman, AK Godfrey, H Skaletsky, DW Bellott… - Cell genomics, 2023 - cell.com
… identified 10 X chromosome genes most likely to drive sex differences in common disease
and sex chromosome aneuploidy syndromes. We conclude that human X chromosomes are …

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer

R Chaligné, T Popova, MA Mendoza-Parra… - Genome …, 2015 - genome.cshlp.org
inactive X chromosome in the context of breast cancer and establishes that epigenetic erosion
of the inactive X … the possibility of exploiting the inactive X chromosome as an epigenetic …

[HTML][HTML] Expression of genes from the human active and inactive X chromosomes

CJ Brown, L Carrel, HF Willard - The American Journal of Human Genetics, 1997 - cell.com
… expressed from both the active and inactive X chromosomes. The growing number of genes
… status of X-linked genes. Since many features of the active or inactive X chromosome, …

X-chromosome inactivation in mammals

E Heard, P Clerc, P Avner - Annual review of genetics, 1997 - annualreviews.org
… The inactive X chromosome differs from the active X in a number of ways;some of these,
such as allocyclic replication and altered histone acetylation,are associated with all types of …