… is established during the reprogramming of somatic … reprogramming. Here, we review
recent advances in the understanding of Xi reactivation during development and reprogramming …

… iPSCs have two active X chromosomes, indicating that reprogramming of mouse somatic …
of the inactive X chromosome can illuminate the processes resulting in reprogramming to …

… paternal or maternal X chromosome early in development. In turn, … silencing, cellular
reprogramming, pluripotency, development, … of the randomly inactivated X chromosome can also …

… Kratzer and Chapman used electrophoretic profiles of the G6PD enzyme dimer to determine
the state of the X chromosome during germ cell development in the mouse species Mus …

… The inactive X (Xi) chromosome can be identified easily by a coating of the long … X is
inactivated, and random, where either X is inactivated. At two points in mouse development…

… be easily reprogrammed to direct embryonic development. On … A fuller biochemical
characterization of the X chromosomes … to which reprogramming of the inactive X chromosome in …

… reprogramming process by examining the means by which reprogramming leads to X
chromosome … Analyzing single cells in situ, we found that hallmarks of the inactive X (Xi) change …

… reprogramming in vitro. Although reprogramming provides a useful model for inactive X (Xi) …
reprogramming, we developed an approach to allow gene expression from each of the two …

… the X chromosome state throughout reprogramming, with an initial robust reactivation of the
inactive X chromosome … Only cells that are committed to developing as primordial germ cells (…

… As such, somatic cell reprogramming serves as an excellent … reprogramming is reactivation
of the inactive X chromosome (… during early embryonic development of female eutherian …