… Interestingly, this phenotype is similar to but slightly less severe than that seen when the
integrin β1 subunit is selectively deleted in the same cell type, 5 , 6 suggesting that …

… The majority are β1 integrins, associated with the α1, α2, α3, α6 or α8 … integrin subunit has
been found in association with the β1, β3, β5 and β6 subunits [1,2] , but it is the αvβ3 integrin …

… α 6 β 1 - and smaller amounts of α 3 β 1 -integrin. The α 6 β 1 - and α 3 β 1 -integrins were
… far no genetic kidney disease has been mapped near the α 3 -integrin human chromsomal …

… integrins could establish a pathologic autostimulatory loop, we tested the role of integrin-β1
in … had higher levels of integrin-β1 and fibronectin and displayed increased integrin-mediated …

… Besides, due to the critical role of integrins such as integrin αvβ6 and β1 on TECs, integrin
carried by exosomes may play an important role in interstitial inflammation and fibrosis. …

… integrin β6, we detected the expression of integrin αv and β6 in db/m and db/db cortices.
Compared to those in the db/m group, the levels of integrin … integrin αv subunit can bind to β1, β3…

… of Integrin β8 in renal pericytes of diabetic kidney disease (DKD). We showed the down-regulated
Integrin … in DKD through TGF-β1/TGFBR1/Smad3 signaling pathway. Overexpression …

… Decreased expression of α3β1 integrin is demonstrated in human diabetic kidney disease,
… Integrin β1 binds to the ILK via its cytoplasmic domain (Hannigan et al., 1996). Integrin-…

… The overexpression of TGF-β1 has been linked with pathological alterations characteristic
of various kidney diseases. In human glomerular disease, TGF-β1 has been reported as a key …

… Epithelial cells adhere to Ln-5 via two adhesive structures, focal adhesions and
hemidesmosomes, through binding to α 3 β 1 or α 6 β 1 and α 6 β 4 integrins, respectively. On …