Ionizing radiation induces transgenerational effects of DNA methylation in zebrafish

JH Kamstra, S Hurem, LM Martin, LC Lindeman… - Scientific reports, 2018 - nature.com
… In this study, we analysed DNA methylation across the entire genome in F1 zebrafish embryos
from irradiated parents. Our results revealed large-scale changes in the DNA methylome, …

Zebrafish as an in vivo model to assess epigenetic effects of ionizing radiation

EY Kong, SH Cheng, KN Yu - International Journal of Molecular Sciences, 2016 - mdpi.com
… In the present review, the epigenetic effects of IR studied or potentially assessed using the
zebrafish model included DNA methylation, histone modifications and miRNA expression, …

Ionising radiation induces promoter DNA hypomethylation and perturbs transcriptional activity of genes involved in morphogenesis during gastrulation in zebrafish

S Murat El Houdigui, C Adam-Guillermin… - International Journal of …, 2020 - mdpi.com
… To check if such processes might occur in our exposure scenario, the DNA methylation level
… present in zebrafish [32] was checked. No change in DNA methylation was detected in DNA

Parental exposure to gamma radiation causes progressively altered transcriptomes linked to adverse effects in zebrafish offspring

S Hurem, LM Martín, L Lindeman, DA Brede… - Environmental …, 2018 - Elsevier
… The exact function of cyp2x6 is currently unknown in zebrafish, but our results indicate the
responsiveness of this gene to ionizing radiation. Cytochrome P450 enzymes are known to be …

Gamma radiation induces locus specific changes to histone modification enrichment in zebrafish and Atlantic salmon

LC Lindeman, JH Kamstra, J Ballangby, S Hurem… - PLoS …, 2019 - journals.plos.org
ionizing radiation in fish. Direct exposure of zebrafish (Danio rerio) embryos to gamma radiation
(… Furthermore, the genome wide alteration of DNA methylation observed in F1 embryonic …

Dose-dependent effects of gamma radiation on the early zebrafish development and gene expression

S Hurem, LM Martín, DA Brede, E Skjerve… - PloS one, 2017 - journals.plos.org
DNA damage [71], but was also demonstrated to be a critical factor for normal development
and survival in zebrafish embryos after exposure to ionizing radiation [… /3 DNA complexes [74]…

Evaluation of epigenetic and radiomodifying effects during radiotherapy treatments in zebrafish

G Pucci, GI Forte, V Cavalieri - International Journal of Molecular …, 2021 - mdpi.com
… them by ionizing radiation. This review aims to provide the literature state of the art of
zebrafish in vivo … In zebrafish, epigenetic marks such as DNA methylation, histone post-translational …

Influence of LED lights on global DNA methylation in Zebrafish (Danio rerio) during maturation phase.

A Chourasia, RK Pradhan - South Asian Journal of …, 2020 - search.ebscohost.com
Ionising radiation (IR) and Non-ionising radiation are the two crucial forms of radiation.
Although IR has therapeutic importance in the treatment of cancer (Poortmans, 2007; Offersen et …

Embryos of the zebrafish Danio rerio in studies of non-targeted effects of ionizing radiation

VWY Choi, KN Yu - Cancer letters, 2015 - Elsevier
… of the zebrafish Danio rerio as the in vivo model for non-targeted effects of ionizing radiation
on an … First, an introduction to the general use of embryos of zebrafish (D. rerio) as an in vivo …

Depleted uranium induces sex-and tissue-specific methylation patterns in adult zebrafish

K Gombeau, S Pereira, JL Ravanat, V Camilleri… - … Radioactivity, 2016 - Elsevier
… relevant concentrations of DU modifies DNA methylation in the zebrafish, and the possible
… Other studies also highlighted significant impacts of ionizing radiation in mice chronically or …