Mucin-type glycoproteins

GJ Strous, J Dekker - Critical reviews in biochemistry and …, 1992 - Taylor & Francis
… 76 and human respiratory mucin were Solid proof for the “windmill” model is lacking. However,
… The genetic polymorphism has direct consequences for the size of mucins produced. This …

[HTML][HTML] Mucins in the mucosal barrier to infection

SK Linden, P Sutton, NG Karlsson, V Korolik… - Mucosal …, 2008 - Elsevier
Mucin glycoproteins produced by mucus-producing cells in the epithelium or … mucin genes
appear to undergo alternative splicing and also encode directly secreted isoforms lacking

Altered mucin expression in the gastrointestinal tract: a review

JR Jass, MD Walsh - Journal of cellular and molecular …, 2001 - Wiley Online Library
… O-acetylation of sialic acid is under genetic control and, as noted above, sialic acid lacking
O… mucin production has been considered [99]. The main secretory mucin MUC5B is produced

Mucin-type O-glycans and their roles in intestinal homeostasis

KSB Bergstrom, L Xia - Glycobiology, 2013 - academic.oup.com
… The importance of core 1-derived O-glycans is further underscored with the study of mice
lacking the … fragilis and production of commensal-derived symbiotic molecules such as PSA. …

Mucus barrier, mucins and gut microbiota: the expected slimy partners?

P Paone, PD Cani - Gut, 2020 - gut.bmj.com
… invasion by increasing mucus production and occupying the binding sites available on the
… For example, it has been observed that in mice lacking MUC2 mucin, the colon was invaded …

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

GC Hansson, MEV Johansson - Gut microbes, 2010 - Taylor & Francis
… The major mucin produced in the small and large intestine is called MUC2. This … are not
observed in wild type animals. The mice lacking the Muc2 mucin develop loose stools, diarrhea …

Secretory IgA and mucin-mediated biofilm formation by environmental strains of Escherichia coli: role of type 1 pili

RR Bollinger, ML Everett, SD Wahl, YH Lee… - Molecular …, 2006 - Elsevier
lacking type 1 pili failed to form SIgA-mediated biofilms, indicating the importance of the type
1 … coli MG1655 lacking the ability to produce type 1 pilus fails to produce a biofilm on live …

[HTML][HTML] … neoformans infection in mice lacking type I interferon signaling leads to increased fungal clearance and IL-4-dependent mucin production in the lungs

K Sato, H Yamamoto, T Nomura, I Matsumoto… - PLoS …, 2015 - journals.plos.org
mucin production in IFNAR1KO mice To clarify the relationship between mucin and IL-4, the
production … anti-IL-4 mAb on the mucin production and the expression of MUC5AC mRNA in …

[HTML][HTML] Characterizing the mucin-degrading capacity of the human gut microbiota

JS Glover, TD Ticer, MA Engevik - Scientific reports, 2022 - nature.com
mucin-degrading capability of 23 representative gut microbes using a chemically defined
media lacking … The intestinal mucus layer is produced by specialized cells known as goblet cells…

Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases

M Andrianifahanana, N Moniaux, SK Batra - Biochimica et Biophysica Acta …, 2006 - Elsevier
types of cancers and inflammatory disorders. It is, therefore, crucial to comprehend the underlying
basis of molecular mechanisms controlling mucin production … of mucin production, with …