The DNA methylation landscape in cancer

K Skvortsova, C Stirzaker, P Taberlay - Essays in biochemistry, 2019 - portlandpress.com
… into DNA methylation dynamics and remodeling in tumorigenesis. In this review, we describe
the distribution of DNA methylation and DNA … Finally, we discuss DNA methylation profiling …

The landscape of DNA methylation amid a perfect storm of autism aetiologies

AV Ciernia, J LaSalle - Nature reviews neuroscience, 2016 - nature.com
… Epigenetic mechanisms such as DNA methylationDNA methylation are providing valuable
mechanistic insights into ASD. The dynamic developmental landscape of DNA methylation is …

[HTML][HTML] Navigating the DNA methylation landscape of cancer

A Nishiyama, M Nakanishi - Trends in Genetics, 2021 - cell.com
DNA methylation patterns are maintained by the daughter DNA through a maintenance
DNA methylation … Both de novo DNA methylation and maintenance DNA methylation are …

Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation

AM Cotton, EM Price, MJ Jones… - Human molecular …, 2015 - academic.oup.com
… We examined the interplay of DNA methylation (DNAm) with CpG density, transcriptional
activity and chromatin state at genes on the X chromosome using over 1800 female samples …

The genome-wide landscape of DNA methylation and hydroxymethylation in response to sleep deprivation impacts on synaptic plasticity genes

R Massart, M Freyburger, M Suderman… - Translational …, 2014 - nature.com
… marks: DNA methylation and hydroxymethylation. DNA methylation differences were enriched
… These data reveal that acute SD reprograms the epigenetic landscape, providing a unique …

The DNA methylation landscape of advanced prostate cancer

SG Zhao, WS Chen, H Li, A Foye, M Zhang… - Nature …, 2020 - nature.com
DNA methylation is a key regulator of gene expression, the comprehensive methylation
landscape of … We also identified intergenic regions where methylation is associated with RNA …

DNA methylation landscapes: provocative insights from epigenomics

MM Suzuki, A Bird - Nature reviews genetics, 2008 - nature.com
… e | The DNA methylation landscape of plants with large genomes, such as maize, has not
been mapped in detail, but it is evident that genes are separated by long tracts of DNA that …

Charting a dynamic DNA methylation landscape of the human genome

MJ Ziller, H Gu, F Müller, J Donaghey, LTY Tsai… - Nature, 2013 - nature.com
… In this study, we systematically investigated the DNA methylation state of most human … On
a global scale, human ES cells and their derivatives exhibit the highest DNA methylation levels…

An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging

T Yuan, Y Jiao, S de Jong, RA Ophoff, S Beck… - PLoS …, 2015 - journals.plos.org
… Importantly, we demonstrate the feasibility of integrating Illumina 450k DNA methylation
with ENCODE data to identify transcription factors with key roles in cellular development and …

Reversible regulation of promoter and enhancer histone landscape by DNA methylation in mouse embryonic stem cells

AD King, K Huang, L Rubbi, S Liu, CY Wang, Y Wang… - Cell reports, 2016 - cell.com
… , we set out to understand how DNA methylation shapes the histone landscape and transcriptome
in mESCs. To study this, we employed sets of mESC with fully methylated and globally …