Function and information content of DNA methylation
D Schübeler - Nature, 2015 - nature.com
… assign a function to the local presence of DNA methylation at particular genes has remained
… function of DNA methylation in mammals, and discusses the utility of DNA methylation as a …
… function of DNA methylation in mammals, and discusses the utility of DNA methylation as a …
DNA methylation in Arabidopsis has a genetic basis and shows evidence of local adaptation
… Here we investigate DNA methylation … CHH methylation was found to increase with
temperature. Genome-wide association studies (GWAS) revealed that the extensive CHH …
temperature. Genome-wide association studies (GWAS) revealed that the extensive CHH …
DNA methylation in human epigenomes depends on local topology of CpG sites
… enzymes that can act on CpGs over an extended local region, while … methylation status,
would allow systematic determination of the general geometric rules for DNA methylation…
would allow systematic determination of the general geometric rules for DNA methylation…
Daily variation in global and local DNA methylation in mouse livers
L Xia, S Ma, Y Zhang, T Wang, M Zhou, Z Wang… - PloS one, 2015 - journals.plos.org
… Previous studies have reported that DNA methylation in human blood shows 24-h variation
[… the DNA methylation state [31]. In this study, we found that global DNA methylation level in …
[… the DNA methylation state [31]. In this study, we found that global DNA methylation level in …
DNA methylation has a local effect on transcription and histone acetylation
RA Irvine, IG Lin, CL Hsieh - Molecular and cellular biology, 2002 - Taylor & Francis
… Our findings with stable episomes in human cells support the view that DNA methylation
affects transcription locally and that the impact on transcription is negligible when methylation is …
affects transcription locally and that the impact on transcription is negligible when methylation is …
New concepts in DNA methylation
A Jeltsch, RZ Jurkowska - Trends in biochemical sciences, 2014 - cell.com
… DNA methylation at each site is determined by the local … Second, we present a modified
stochastic DNA methylation … de novo and the maintenance methylation process at CpG and non-…
stochastic DNA methylation … de novo and the maintenance methylation process at CpG and non-…
Genome-wide evidence for local DNA methylation spreading from small RNA-targeted sequences in Arabidopsis
… DNA methylation (RdDM) machinery. We provide evidence that these TE sequences acquire
DNA methylation … we propose that spreading of DNA methylation through promoter regions …
DNA methylation … we propose that spreading of DNA methylation through promoter regions …
Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles
… DNA methylation profiles locally [15,16], we hypothesized that the disruption of TFBSs by rare
SNVs can modify local DNA methylation … we combined blood DNA methylation profiles and …
SNVs can modify local DNA methylation … we combined blood DNA methylation profiles and …
The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood
… of the potential for local sequence features and genomic context to influence the methylation
state of CpGs will enhance our comprehension of how DNA methylation is regulated under …
state of CpGs will enhance our comprehension of how DNA methylation is regulated under …
Natural variation of DNA methylation and gene expression may determine local adaptations of Scots pine populations
E Alakärppä, HM Salo, L Valledor… - Journal of …, 2018 - academic.oup.com
… genes, which maintain DNA methylation. The expression of … which suggests a role for DNA
methylation in local adaptation. For … DNA methylation and gene expression contribute to local …
methylation in local adaptation. For … DNA methylation and gene expression contribute to local …