[HTML][HTML] Passive and active DNA methylation and the interplay with genetic variation in gene regulation

M Gutierrez-Arcelus, T Lappalainen, SB Montgomery… - elife, 2013 - elifesciences.org
DNA methylation may delineate a platform in which local inter… genetic regulatory variation,
DNA methylation alone does not … and active role of DNA methylation to regulatory interactions …

[HTML][HTML] DNA methylation, nuclear organization, and cancer

BP Madakashira, KC Sadler - Frontiers in genetics, 2017 - frontiersin.org
… of DNA methylationDNA methylation in cancer has focused on how local changes contribute
to gene expression. However, the emerging picture is that the changes to DNA methylation

[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics

S Li, Y Peng, AR Panchenko - Current opinion in structural biology, 2022 - Elsevier
… It should be noted that the magnitude of effects caused by CpG methylation strongly
depends on the local DNA sequence context around the methylated site [19]. For example, an …

Quantitative comparison of within-sample heterogeneity scores for DNA methylation data

M Scherer, A Nebel, A Franke, J Walter… - Nucleic acids …, 2020 - academic.oup.com
local deep amplicon sequencing can be used to reconstruct the probability distribution of
DNA methylation … the concept of locally disordered DNA methylation patterns (24) to quantify …

Principles of DNA methylation and their implications for biology and medicine

Y Dor, H Cedar - The Lancet, 2018 - thelancet.com
… In this Review we provide a map of the DNA methylation landscape, … We also discuss how
DNA methylation could provide a … Taken together, these changes make the local environment …

Identification of DNA motifs that regulate DNA methylation

M Wang, K Zhang, V Ngo, C Liu, S Fan… - Nucleic Acids …, 2019 - academic.oup.com
… The CTCF’s critical role in affecting the local DNA methylation in these loci was
confirmed and we indeed found that CTCF and UMs were even more enriched at these loci (…

[HTML][HTML] Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity

SM Linker, L Urban, SJ Clark, M Chhatriwala, S Amatya… - Genome biology, 2019 - Springer
… on local sequence composition and genomic features. We observe moderate but consistent
contributions from local DNA methylation … as well as DNA methylation information accurately …

[HTML][HTML] Genome-wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis

T Fleischer, A Frigessi, KC Johnson, H Edvardsen… - Genome biology, 2014 - Springer
DNA methylation patterns are also associated with … conserving surgery (that is, wide local
resection or sector resection) or … a local recurrence after 15 years follow-up and the risk of local

Deciphering the genetic code of DNA methylation

M Wang, V Ngo, W Wang - Briefings in bioinformatics, 2021 - academic.oup.com
… The molecular mechanisms described above have laid the foundation for many studies that
use genetic features to predict local DNA methylation. These studies have shed light on the …

[HTML][HTML] Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma

E Hervouet, P Peixoto, R Delage-Mourroux… - Clinical …, 2018 - Springer
… Our current view of DNA methylation processes is strongly … novo methylation and DNMT1 is
associated with inheritance DNA … are highly related but are dependent of both, the local DNA