DNA methylation has a local effect on transcription and histone acetylation

RA Irvine, IG Lin, CL Hsieh - Molecular and cellular biology, 2002 - Taylor & Francis
… We also examined the histones associated with different … affects the state of histone acetylation
in the adjacent unmethylated … the state of histone acetylation appears to be a local effect. …

Histone acetylation and transcriptional regulatory mechanisms

K Struhl - Genes & development, 1998 - genesdev.cshlp.org
… the region where histone acetylation or deacetylation occurs. … Furthermore, local perturbations
of chromatin structure could … parameters and the local state of histone acetylation. Thus, to …

Histone acetylation and an epigenetic code

BM Turner - Bioessays, 2000 - Wiley Online Library
… In such mutants, transient expression of HO in late G1 occurred essentially as normal, but
was not accompanied by any local changes in histone acetylation. In contrast, these mutants …

Local histone acetylation by ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy

X Li, X Qian, Z Lu - Autophagy, 2017 - Taylor & Francis
… In the nuclei of GBM cells, ACSS2 forms complexes with TFEB, a master regulator of lysosomal
and autophagy-related genes, and locally produces acetyl-CoA for histone acetylation in …

Role of histone acetylation in cell cycle regulation

M Koprinarova, M Schnekenburger… - Current topics in …, 2016 - ingentaconnect.com
… The dynamics of local or global histone acetylation is associated with fundamental cellular
processes such as gene transcription, DNA replication, DNA repair or chromatin condensation…

Histone acetylation: truth of consequences?

JK Choi, LAJ Howe - Biochemistry and Cell Biology, 2009 - cdnsciencepub.com
… of histone acetylation marks, however, we often lose sight of the question: how does histone
acetylation … of histone acetylation: that it directly alters chromatin structure by weakening …

DNA methylation models histone acetylation

S Eden, T Hashimshony, I Keshet, H Cedar, AW Thorne - Nature, 1998 - nature.com
local histone acetylation states. After replication, newly deposited histones in unmethylated
regions may undergo acetylationHistone acetylation is a fundamental regulatory mechanism …

Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors

Y Katan-Khaykovich, K Struhl - Genes & development, 2002 - genesdev.cshlp.org
… Targeted acetylases and deacetylases can locally … of histone acetylation. Our results also
indicate that TBP occupancy depends on the presence of the activator, not histone acetylation

Replication-independent nucleosome exchange is enhanced by local and specific acetylation of histone H4

GO Elliott, KJ Murphy, JJ Hayes… - Nucleic acids research, 2013 - academic.oup.com
… Our results support a model whereby histone acetylation on K8 and K16 specifically … with
histone acetylation, we asked whether this modification is associated with the observed histone

Long-range histone acetylation: biological significance, structural implications, and mechanisms

A Calestagne-Morelli, J Ausio - Biochemistry and cell biology, 2006 - cdnsciencepub.com
acetylation across the domain in question. Here we review the characteristics of long-range
histone acetylation … literature on the multiple effects that histone hyperacetylation has on …