Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function

W Qiu, A Baccarelli, VJ Carey, N Boutaoui… - American journal of …, 2012 - atsjournals.org
… We propose that the investigation of DNA methylation marks in subjects with and without a …
to lung function decline/COPD. To pursue this hypothesis we conducted methylation screens, …

Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

M Machin, AFS Amaral, M Wielscher, FI Rezwan… - BMC pulmonary …, 2017 - Springer
… Three of the six articles assessed the association of COPD with DNA methylation, and … lung
function. Overall, five reports examined the association of lung function with DNA methylation

From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function

M de Vries, DA van der Plaat, I Nedeljkovic… - Respiratory …, 2018 - Springer
… with lower lung function levels [15, 16]. Hence, we postulate that DNA methylation plays an
… mediating the effect that cigarette smoking has on lung function levels. In this study, we aim …

DNA methylation is associated with lung function in never smokers

M de Vries, I Nedeljkovic, DA van der Plaat… - Respiratory …, 2019 - Springer
… differential DNA methylation associated with lung function in … with a continuous measurement
of lung function, we might be … association between DNA methylation and lung function in …

Changes of DNA methylation are associated with changes in lung function during adolescence

SK Sunny, H Zhang, FI Rezwan, CL Relton… - Respiratory …, 2020 - Springer
… period for the gender-dependent development of lung function. Prior studies have shown
that DNA methylation (DNA-M) is associated with lung function and DNA-M at some cytosine-…

DNA methylation at birth is associated with lung function development until age 26 years

N Mukherjee, R Arathimos, S Chen… - European …, 2021 - Eur Respiratory Soc
Little is known about whether DNA methylation (DNAm) of cytosine–phosphate–guanine (CpG)
sites at birth predicts patterns of lung function development. We used heel prick DNAm …

Pulmonary function and blood DNA methylation: a multiancestry epigenome-wide association meta-analysis

M Lee, T Huan, DL McCartney, G Chittoor… - American Journal of …, 2022 - atsjournals.org
… of blood DNA methylation and pulmonary function identified … mechanisms regulating
pulmonary function. Some preliminary … COPD in lung tissue (36) in our lung function meta-analyses. …

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course

HT den Dekker, K Burrows, JF Felix… - European …, 2019 - Eur Respiratory Soc
DNA methylation in the identified DMRs in the same individuals from birth to adulthood. In a
recent study addressing DNA methylation … of DNA methylation with asthma or lung function. …

Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood

SK Sunny, H Zhang, F Mzayek, CL Relton, S Ring… - Clinical …, 2021 - Springer
lung function trajectories, the importance of DNA methylation (DNA-M), and the critical role
of adolescence in lung function … of pre-adolescent DNA-M with lung function trajectories. This …

Long-term air pollution exposure, genome-wide DNA methylation and lung function in the LifeLines cohort study

AJ de FC Lichtenfels, DA Van Der Plaat… - Environmental …, 2018 - ehp.niehs.nih.gov
… to confirm our hypothesis that NO 2 exposure may affect lung function through effects on
DNA methylation. Among the seven differentially methylated CpG sites, two showed suggestive …