… the DNMT1/UHRF1 complex in maintenance DNA methylation (Figure 4): (i) The UHRF1 TTD
… These intramolecular interactions lock UHRF1 in a closed conformation and keep it in an …

… of maintenance DNA methylation and DNA replication by Uhrf1, we first reconstituted
maintenance DNA methylation … After DNA replication, genomic DNA purified from sperm chromatin …

… of DNMT1 and maintenance of DNA methylation. Collectively, our … by UHRF1 and supports
that individual domains of UHRF1 participate and act in concert to maintain DNA methylation …

… Here we show that UHRF1 association with methylated histone H3 Lys9 (H3K9) is … for DNA
methylation maintenance. We further show that UHRF1 association with H3K9 methylation is …

… that UHRF1 is required for maintenance of CG DNA methylation, … UHRF1 SRA domain
for hemimethylated DNA suggests a model in which UHRF1 can bind to hemimethylated DNA …

… The maintenance of DNA methylation mediated by UHRF1–DNMT1 complex is involved
in the regulation of many vital activities. This review describes the whole molecular process …

… methyltransferase 1 (DNMT1) to maintain DNA methylation in both … DNA reader domains
of UHRF1 are critical functional determinants for maintaining cancer-specific DNA methylation …

… repair processes. We focus on the most recent findings about the different roles of UHRF1
in the DNA damage repair, … function of UHRF1 is the DNA methylation maintenance, that …

… We examined the role of UHRF1, a protein essential for the maintenance of CG methylation
in somatic cells, in oocytes and preimplantation embryos by generating oocyte-specific Uhrf1 …

… It follows that every CpG that was symmetrically methylated before … fully methylated state is
called “maintenance DNA methylation”, and it involves two key actors: DNMT1 and UHRF1 4 . …