… of DNA methylation patterns remain under investigation. Here, we review the field of DNA
methylation from its beginning to present day, with an emphasis on findings in mammalian …

… mammalian development. Its perturbation is often associated with human diseases. In mammalian
genomes, DNA methylation … including early embryonic development and in embryonic …

… in DNA methylation has been created by increasing evidence that links methylation patterns
… An inverse correlation between methylation and transcriptional activity has been found for a …

… differences in overall levels of human DNA methylation and the extent of transcriptional …
of DNA methylation in eucaryotes, we have analyzed the 5-methylcytosine content of DNA for …

… DNA methylation is extensively reprogrammed during the early phases of mammalian
development, yet genomic targets of this process are largely unknown. We optimized …

… In mammals, DNA methylation and the modification of histones … Two cycles of DNA methylation
reprogramming have been … Mammalian development is characterised by bimodal DNA …

… For a long time DNA methylation at CpG sites in mammals had been considered a paradigm
of epigenetic information transfer, because its molecular mechanism of inheritance was …

Aging, often considered a result of random cellular damage, can be accurately estimated
using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we …

In mouse and most other mammalian species, the paternal and maternal genomes undergo
parent-specific epigenetic reprogramming during preimplantation development. The …

… There is strong evidence that DNA methylation plays an important role in the control of gene
… mammalian cells, and the properties of a CHO mutant strain affected in DNA methylation are …