DNA methylation and mammalian epigenetics

W Reik, W Dean - Electrophoresis, 2001 - Wiley Online Library
… of epigenetic inheritance through the germline [14]. Again, more examples of epigenetic
the recent developments in mammalian epigenetics and methylation and hope this provides …

The role of DNA methylation in mammalian epigenetics

PA Jones, D Takai - Science, 2001 - science.org
DNA methylation is essential for the development of mammals (1, 2), but despite 25 years of
… characterization of the three known active DNA cytosine methyltransferases (DNMT1, -3a, …

Mammalian epigenetic mechanisms

G Zhang, S Pradhan - IUBMB life, 2014 - Wiley Online Library
DNA methylation is the most commonly studied epigenetic mark in the mammalian genome.
It is primarily thought to suppress the binding of transcription factors to gene promoters, thus …

DNA methylation in mammals

E Li, Y Zhang - Cold Spring Harbor perspectives in …, 2014 - cshperspectives.cshlp.org
DNA methylation is one of the best characterized epigenetic modifications. In mammals it is
… This article describes how DNA methylation serves as a cellular memory system and how it …

DNA methylation: roles in mammalian development

ZD Smith, A Meissner - Nature Reviews Genetics, 2013 - nature.com
methylation … of DNA methylation in mammals, stemming from more than two decades of
research, including many recent studies that have elucidated when and where DNA methylation

DNA methylation patterns and epigenetic memory

A Bird - Genes & development, 2002 - genesdev.cshlp.org
… is tempered by this sequence disparity, and by the absence so far of a clear demonstration
that mammalian double-stranded RNA leads to DNA methylation-mediated gene silencing. …

Maintenance and regulation of DNA methylation patterns in mammals

Z Chen, AD Riggs - Biochemistry and cell biology, 2005 - cdnsciencepub.com
… progress in understanding the regulation of mammalian DNA methylation patterns, with an
emphasis … methylation and discuss its implications for epigenetic fidelity and gene regulation. …

[HTML][HTML] The cell biology of DNA methylation in mammals

E Prokhortchouk, PA Defossez - … et Biophysica Acta (BBA)-Molecular Cell …, 2008 - Elsevier
… of epigenetic phenomena in general, and DNA methylation in … out the connections between
DNA methylation and nuclear … The study of DNA methylation, its effectors, and its roles, …

DNA methylation and epigenetic mechanisms

R Holliday - Cell biophysics, 1989 - Springer
… There is strong evidence that DNA methylation plays an important role in the control of gene
mammalian cells, and the properties of a CHO mutant strain affected in DNA methylation are …

The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
mammalian development. We also discuss new insights gained into the patterning of DNA
methylation … current views of the diverse functions of DNA methylation in genetic diseases. …