[HTML][HTML] Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease
… Another study has shown that microglia, the brain’s resident macrophages, display a greater
than fourfold increase in ANK1 expression in AD compared to control brain samples [26], …
than fourfold increase in ANK1 expression in AD compared to control brain samples [26], …
Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1
P Cronin, MJ McCarthy, ASP Lim, DP Salmon… - Alzheimer's & …, 2017 - Elsevier
… We investigated whether aberrant DNA methylation contributes to circadian deregulation. …
and matched control subjects, we provide strong evidence for a role of DNA methylation cycles …
and matched control subjects, we provide strong evidence for a role of DNA methylation cycles …
Prediction of Alzheimer's disease based on deep neural network by integrating gene expression and DNA methylation dataset
… Especially, DNA methylation is well known as a molecular factor that can control and
regulate the level of expression of genes located nearby in the CpG site. Conventional feature …
regulate the level of expression of genes located nearby in the CpG site. Conventional feature …
Abnormal homocysteine metabolism: an insight of Alzheimer's disease from DNA methylation
T Pi, B Liu, J Shi - Behavioural Neurology, 2020 - Wiley Online Library
… [145] analyzed the effect of SAM administration on the expression of 588 central nervous …
genes had DNA methylation upregulated and four genes had DNA methylation downregulated […
genes had DNA methylation upregulated and four genes had DNA methylation downregulated […
Global long interspersed nuclear element 1 DNA methylation in a Colombian sample of patients with late-onset Alzheimer's disease
HG Hernández, MF Mahecha, A Mejía… - … of Alzheimer's …, 2014 - journals.sagepub.com
… Alzheimer’s disease (LOAD). The objective of this work was to evaluate global DNA methylation
… with LOAD and control participants. Our findings are in disagreement with a previous …
… with LOAD and control participants. Our findings are in disagreement with a previous …
[HTML][HTML] Epigenetics of Alzheimer's disease
… the effect of DNA methylation and DNA hydroxymethylation in AD patients (Table 1 and …
with MCI group and cognitively normal control and/or other disease control subjects), sample size…
with MCI group and cognitively normal control and/or other disease control subjects), sample size…
Altered CpG methylation in sporadic Alzheimer's disease is associated with APP and MAPT dysregulation
… methylation status remained stable for 24 h post-mortem, which provides good rational
for studying DNA methylation … show normal control (NC) plotted on Alzheimer's disease (AD) …
for studying DNA methylation … show normal control (NC) plotted on Alzheimer's disease (AD) …
[HTML][HTML] The role of DNA methylation and histone modifications in neurodegenerative diseases: a systematic review
… global DNA methylation by calculating the amount of methylated … a positive control. Other
methods to assess global genomic … Global changes in DNA methylation in Alzheimer's disease …
methods to assess global genomic … Global changes in DNA methylation in Alzheimer's disease …
Integrated whole transcriptome and DNA methylation analysis identifies gene networks specific to late-onset Alzheimer's disease
CE Humphries, MA Kohli, L Nathanson… - … of Alzheimer's …, 2015 - content.iospress.com
… DNA methylation and splicing. In this study, we identify differentially transcribed and spliced
genes within networks and DNA methylation … relative to our disease control, we compared …
genes within networks and DNA methylation … relative to our disease control, we compared …
Epigenetics in Alzheimer's disease: a focus on DNA modifications
N Coppieters, M Dragunow - Current pharmaceutical design, 2011 - ingentaconnect.com
… of the disease. In this review we focus on discussing the roles of DNA methylation and …
levels at the CpG sites investigated did not vary between AD brains and control brains [121]. …
levels at the CpG sites investigated did not vary between AD brains and control brains [121]. …