… methylation in the NCAPH2/LMF2 promoter region is associated with hippocampal atrophy in Alzheimer's disease and amnesic mild cognitive impairment patients

S Shinagawa, N Kobayashi, T Nagata, A Kusaka… - Neuroscience …, 2016 - Elsevier
… Several studies have noted an effect of DNA methylation on the pathogenesis of Alzheimer’s
disease (AD). We have already reported that DNA methylation levels in the NCAPH2/LMF2 …

Epigenetic changes in the progression of Alzheimer's disease

MA Bradley-Whitman, MA Lovell - Mechanisms of ageing and development, 2013 - Elsevier
… , DNA methylation status is considered static following widespread and dynamic alterations
in methylation … ) in normal control (NC) subjects and late-stage Alzheimer's disease (LAD). …

[HTML][HTML] Advances in genetics and epigenetic alterations in Alzheimer's disease: a notion for therapeutic treatment

R Rabaneda-Bueno, B Mena-Montes, S Torres-Castro… - Genes, 2021 - mdpi.com
… In blood samples from patients with AD and the control subjects, as well as in individuals
with MCI, elevated levels of DNA methylation in the homeobox cluster A (HOXA) and …

Early life exposure to lead (Pb) and changes in DNA methylation: relevance to Alzheimer's disease

SW Bihaqi - Reviews on environmental health, 2019 - degruyter.com
… of US Occupational Safety and Health Administration Pb standards in 1993 articulating that
… Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings …

Decreased methylation of the mitochondrial D-loop region in late-onset Alzheimer's disease

A Stoccoro, G Siciliano, L Migliore… - … of Alzheimer's Disease, 2017 - content.iospress.com
… preclinical stages of AD respect to healthy control individuals, suggesting that the D-… DNA
methylation levels of the mtDNA D-loop region in blood DNA of a large cohort of LOAD patients

[HTML][HTML] DNA methylation biomarkers in aging and age-related diseases

Y Salameh, Y Bejaoui, N El Hajj - Frontiers in Genetics, 2020 - frontiersin.org
… -control array studies compared DNA methylationDNA methylation levels were also observed
in the peripheral blood mononuclear cells of late onset Alzheimer disease (LOAD) patients

A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease

J Zhao, Y Zhu, J Yang, L Li, H Wu, PL De Jager… - Alzheimer's & …, 2017 - Elsevier
DNA methylation is a key epigenetic mechanism in brain aging and Alzheimer's disease (AD).
The newly discovered 5-hydroxymethylcytosine mediates DNA demethylation, is highly …

DNA methylation: The epigenetic mechanism of Alzheimer's disease

HY Qin, JY Liu, CL Fang, YP Deng, Y Zhang - Ibrain, 2023 - Wiley Online Library
DNA methylation to AD. This review focuses on elucidating the relationship between DNA
methylation … Many studies have identified that DNA methylation can control gene expression …

[HTML][HTML] Alzheimer's disease-associated (hydroxy) methylomic changes in the brain and blood

R Lardenoije, JAY Roubroeks, E Pishva, M Leber… - Clinical …, 2019 - Springer
DNA modifications, comparing brain tissue from AD patients and age-matched controls. In
addition, we explored DNA methylation in … and neurologically normal control BBDP donors …

Analysis of SNAP25 mRNA expression and promoter DNA methylation in brain areas of Alzheimer's Disease patients

TK Furuya, PNO Silva, SLM Payão, PHF Bertolucci… - Neuroscience, 2012 - Elsevier
… ΔΔC T method and promoter DNA methylation was quantified by mass … in SNAP25 promoter
DNA methylation were observed … (RNAse-free water) control samples were run in parallel to …