Mechanisms of DNA methylation and demethylation in mammals

G Auclair, M Weber - Biochimie, 2012 - Elsevier
… at the genome level, which revealed that patterns of DNA methylation are highly dynamic …
of DNA methylation for genome regulation and the mechanisms that remodel the DNA

[HTML][HTML] DNA methylation and its basic function

LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
… In this chapter, we would introduce a major epigenetic mechanism involving direct
chemical modification to the DNA called DNA methylation. Historically, DNA methylation was …

[HTML][HTML] Reversing DNA methylation: mechanisms, genomics, and biological functions

H Wu, Y Zhang - Cell, 2014 - cell.com
… or DNA glycosylase-initiated base excision repair. In this review, we discuss the mechanism
and function of DNA … to active reversal of DNA methylation in diverse biological processes. …

[图书][B] DNA Methylation: Basic Mechanisms

W Doerfler, P Böhm - 2006 - books.google.com
… In this review, we focus on the molecules and mechanisms responsible for the replication
and translation of DNA methylation in mammals as one of the central epigenetic marks. …

DNA methylation and epigenetic mechanisms

R Holliday - Cell biophysics, 1989 - Springer
… There is strong evidence that DNA methylation plays an important role in the control of … in
DNA methylation are described. Human diploid cells progressively lose cytosine methylation

DNA methylation

R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… Transcriptional repression in vivo was relieved by the deacetylase inhibitor trichostatin A,
suggesting that two global mechanisms of gene regulation, DNA methylation and histone …

[HTML][HTML] Mechanism of DNA methylation-directed histone methylation by KRYPTONITE

J Du, LM Johnson, M Groth, S Feng, CJ Hale, S Li… - Molecular cell, 2014 - cell.com
DNA methylation is controlled by the H3K9 methylation mark through a self-reinforcing loop
between DNA … We report on the structure of KYP in complex with methylated DNA, substrate …

The role and mechanisms of DNA methylation in the oocyte

G Sendžikaitė, G Kelsey - Essays in Biochemistry, 2019 - portlandpress.com
… of de novo DNA methylation mechanisms in the oocyte: how a distinctive gene-body
methylation pattern is created, and the extent to which the DNA methylation machinery reads …

DNA methylation and cancer development: molecular mechanism

H Akhavan-Niaki, AA Samadani - Cell biochemistry and biophysics, 2013 - Springer
… the mechanism and cell regulatory effects of both hypo- and hyper-DNA methylation on
cancer… the effects of DNA methylation on cancer development. Indeed, alteration of the pattern of …

Staying true to yourself: mechanisms of DNA methylation maintenance in mammals

N Petryk, S Bultmann, T Bartke… - Nucleic acids …, 2021 - academic.oup.com
DNA methylation is essential. Mechanistically, the maintenance of this epigenetic modification
takes place during and after DNAmechanisms, dynamics and fidelity of DNA methylation