DNA methylation, chromatin boundaries, and mechanisms of genomic imprinting

F Recillas-Targa - Archives of Medical Research, 2002 - Elsevier
… of chromatin structure in genomic imprinting? One strong structural candidate is the
differentially methylated region (DMR) that corresponds to a specialized chromatin center of …

[HTML][HTML] Chromatin mechanisms in genomic imprinting

S Kacem, R Feil - Mammalian genome, 2009 - Springer
Chromatin at transcribed regions of the genome is marked by H3 lysine-36 methylation (Mikkelsen
et al. 2007). This unique signature was used recently to map long ncRNAs located …

[PDF][PDF] Mechanisms of genomic imprinting

K Pfeifer - The American Journal of Human Genetics, 2000 - cell.com
imprinted genes represents a clear situation in which epigenetic mechanisms restrict gene
… the role of DNA modifications and chromatin structure in maintaining appropriate patterns of …

Setting up and maintaining differential insulators and boundaries for genomic imprinting

A Murrell - Biochemistry and Cell Biology, 2011 - cdnsciencepub.com
… the mechanisms whereby insulator/boundary elements organise the … chromatin structure
mediated by insulators and boundaries associated with genomic elements that control imprinted

Differential 3D chromatin organization and gene activity in genomic imprinting

D Noordermeer, R Feil - Current opinion in genetics & development, 2020 - Elsevier
… At most imprinted domains however, more complex mechanisms are involved that can
affect … chromosome—acts as a chromatin boundary that blocks interactions between regions …

Epigenetic mechanisms of genomic imprinting: common themes in the regulation of imprinted regions in mammals, plants, and insects

WA MacDonald - Genetics research international, 2012 - Wiley Online Library
imprinted regions that could direct chromatin alterations or recruit additional epigenetic
mechanisms. … extending beyond the previously established boundaries of imprinted regions [37]. …

Genomic imprinting: parental influence on the genome

W Reik, J Walter - Nature Reviews Genetics, 2001 - nature.com
… 'reading mechanisms' that convert the imprint into differential gene expression. … chromatin
boundary that is 'closed' when unmethylated, and 'open' when methylated. A specific chromatin

Genomic imprinting: intricacies of epigenetic regulation in clusters

RI Verona, MRW Mann… - Annual review of cell and …, 2003 - annualreviews.org
Genomic imprinting is an epigenetic mechanism of transcriptional regulation through which
… The two parental copies of an imprinted gene often exhibit differential chromatin structure (…

[HTML][HTML] DNA methylation in genomic imprinting

B Tycko - Mutation Research/Reviews in Mutation Research, 1997 - Elsevier
gene expression, DNA methylation has been an attractive candidate for the biochemical
mechanism of genomic imprinting. … the boundaries of these chromatin domains and chromatin

[HTML][HTML] Epigenetic control of the genome—lessons from genomic imprinting

BT Adalsteinsson, AC Ferguson-Smith - Genes, 2014 - mdpi.com
… contribution of genomic imprinting studies to our understanding of epigenetic mechanisms.
… proteins that bring about gene repression through recruitment of chromatin modifiers. A …