Methyl‐CpG‐binding proteins: Targeting specific gene repression
E Ballestar, AP Wolffe - European journal of biochemistry, 2001 - Wiley Online Library
… forms a complex with the DNA mismatch-repair protein MLH1, form complexes with
histone … that MBD proteins are involved in recruiting histone deacetylases to methyl CpG-enriched …
histone … that MBD proteins are involved in recruiting histone deacetylases to methyl CpG-enriched …
Biological functions of methyl-CpG-binding proteins
PA Defossez, I Stancheva - Progress in molecular biology and translational …, 2011 - Elsevier
… unrelated protein folds have the ability to recognize methylated CpGs in … of methyl-CpG-binding
proteins: the MBD protein family, Kaiso and Kaiso-like proteins, and SRA domain proteins…
proteins: the MBD protein family, Kaiso and Kaiso-like proteins, and SRA domain proteins…
The roles of the methyl-CpG binding proteins in cancer
… a methyl-CpG binding protein 1,22 (MeCP1), which was capable of binding at least 12
symmetrically methylated CpGs, … protein capable of binding a single methylated CpG, the 53-kDa …
symmetrically methylated CpGs, … protein capable of binding a single methylated CpG, the 53-kDa …
Methyl CpG‐binding proteins and transcriptional repression
PA Wade - Bioessays, 2001 - Wiley Online Library
… to bind methylated DNA, however, suggests that the ancestral form of this protein was a
bona fide methyl CpG-binding protein, a function lost during the evolution of mammals but …
bona fide methyl CpG-binding protein, a function lost during the evolution of mammals but …
[HTML][HTML] Methyl-CpG binding proteins in the nervous system
G Fan, L Hutnick - Cell research, 2005 - nature.com
… proteins serve as transcriptional repressors, mediating gene silencing via DNA cytosine
methylation. Mutations in methyl-CpG binding protein … role for methyl-CpG binding proteins in …
methylation. Mutations in methyl-CpG binding protein … role for methyl-CpG binding proteins in …
Identification and characterization of a family of mammalian methyl CpG-binding proteins
B Hendrich, A Bird - Genetics Research, 1998 - cambridge.org
… A component of human MeCP1 which binds methylated DNA and is capable of repressing
… the methyl CpG-binding domain (MBD) of MeCP2. This protein was named PCM1 for Protein …
… the methyl CpG-binding domain (MBD) of MeCP2. This protein was named PCM1 for Protein …
Methyl CpG binding proteins: coupling chromatin architecture to gene regulation
PA Wade - Oncogene, 2001 - nature.com
… ), this review will focus instead on proteins that function downstream of the DNA methylation
… featuring DNA methylation, this review will focus on methyl CpG binding proteins in animals. …
… featuring DNA methylation, this review will focus on methyl CpG binding proteins in animals. …
[HTML][HTML] DNA methylation and methyl-CpG binding proteins: developmental requirements and function
O Bogdanović, GJC Veenstra - Chromosoma, 2009 - Springer
… Two families of proteins that bind methylated DNA. a Methyl-CpG binding proteins (MBDs):
MBD proteins display homology within their MBD domains, while the transcription repression …
MBD proteins display homology within their MBD domains, while the transcription repression …
Methyl-CpG binding proteins: specialized transcriptional repressors or structural components of chromatin?
T Clouaire, I Stancheva - Cellular and Molecular Life Sciences, 2008 - Springer
… In this review we focus on the methyl-CpG binding proteins and how they translate DNA …
methyl-CpG binding proteins recognize more complex sequences than a single methylated CpG…
methyl-CpG binding proteins recognize more complex sequences than a single methylated CpG…
Engineering a high-affinity methyl-CpG-binding protein
HF Jørgensen, K Adie, P Chaubert… - Nucleic acids …, 2006 - academic.oup.com
… of artificial methyl-CpG-binding proteins based on … other methyl-CpG-binding proteins for
DNA binding in vitro. When expressed in vivo, the poly-MBD protein localized to the methyl-CpG…
DNA binding in vitro. When expressed in vivo, the poly-MBD protein localized to the methyl-CpG…
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