… was in fact mediated by a methyl-CpG binding protein. We decided therefore to study further
the effect of DNA methylation on transcription of CpG-deficient genes, using promoters of …

… sites for MeCP2 and MBD2, would increase the probability of these proteins to bind, thereby
… Altogether, our data favor a more direct and structural role of methyl CpG–binding proteins …

… The level of mRNA for the DNA methyltransferases and methyl-CpGbinding proteins was …
The level of mRNA for each DNA methyltransferase and methylCpG-binding protein in HCC …

… Here we study the mechanism of repression by MeCP2, an abundant nuclear protein that
is essential for mouse embryogenesis 10 . MeCP2 binds tightly to chromosomes in a …

… CpG dinucleotides. MeCP2 is the founder member of the methyl-CpG-binding domain proteins,
which consists of a single polypeptide that contains a methyl-CpG-binding domain and a …

… Protein coding sequences are indicated by vertical bars and the methyl-CpG binding domain“
by solid black boxes. The shaded area represents a presumed extensive 3' untranslated …

… is transmitted by proteins, which specifically recognize methylated CpGs. The first reported
… proteins is methyl-CpG-binding protein 2 (MeCP2) (1). It can bind to a single methylated CpG …

… inactivation by DNA methylation, we characterized a human MBD1 protein, one of the
components of MeCP1, which possesses a methyl-CpG binding domain (MBD) and cysteine-rich (…

… : (i) methylation at CpG sites that prevents binding of transcription factors and (ii) recognition
of mCpGs by a family of methyl-CpG binding proteins (MBD). Among these proteins, MBD1 …

… Methyl-CpG binding protein 1 (MBD1), a member of the methylated DNA-binding protein
family, has been shown to bind methylated gene promoters and facilitate transcriptional …