Biological functions of methyl-CpG-binding proteins

PA Defossez, I Stancheva - Progress in molecular biology and translational …, 2011 - Elsevier
CpGs in vitro and in vivo. In this chapter, we focus on the three major families of methyl-CpG-binding …
We discuss the structural bases of methyl-CpG recognition, the function and specific …

DNA methylation and methyl-CpG binding proteins: developmental requirements and function

O Bogdanović, GJC Veenstra - Chromosoma, 2009 - Springer
… our understanding of the function of DNA methylation, DNA methyltransferases, and methyl-CpG
binding proteins in vertebrate embryonic development. MBDs function in transcriptional …

The biological functions of the methyl-CpG-binding protein MeCP2 and its implication in Rett syndrome

X Nan, A Bird - Brain and Development, 2001 - Elsevier
… (for methyl-CpG binding protein 2) [8]. Our current knowledge of the biological function of …
In this review we describe the functions of MeCP2 and its relatives, the methyl-CpG-binding …

The roles of the methyl-CpG binding proteins in cancer

L Parry, AR Clarke - Genes & cancer, 2011 - journals.sagepub.com
… This section will cover the functions of the individual members of each family that are … This
review has highlighted the many and intricate roles that MBPs play in human biology. Primarily…

Methyl CpG‐binding proteins and transcriptional repression

PA Wade - Bioessays, 2001 - Wiley Online Library
… While these are likely to be biologically significant regulatory … methyl CpG dinucleotide by a
conserved family of proteins, the … bona fide methyl CpG-binding protein, a function lost during …

Recognition of methylated DNA through methyl-CpG binding domain proteins

X Zou, W Ma, IA Solov'Yov, C Chipot… - Nucleic acids …, 2012 - academic.oup.com
Biological functions of the MBD proteins in epigenetic regulation have been studied over
several … surface contacting mDNA and are responsible for recognition of the methyl-CpG steps. …

Methyl CpG binding proteins: coupling chromatin architecture to gene regulation

PA Wade - Oncogene, 2001 - nature.com
biology (Bestor, 2000; Robertson and Wolffe, 2000; Hendrich and Bird, 2000), this review
will focus instead on proteins that function … focus on methyl CpG binding proteins in animals. …

Methyl-CpG binding proteins: specialized transcriptional repressors or structural components of chromatin?

T Clouaire, I Stancheva - Cellular and Molecular Life Sciences, 2008 - Springer
Biological functions of DNA methylation have been intensively studied over several decades…
genomes include DNA methylation as part of more complex regulatory functions [16, 17]. …

The methyl-CpG binding domain and the evolving role of DNA methylation in animals

B Hendrich, S Tweedie - TRENDS in Genetics, 2003 - cell.com
… number and diversity of methyl-CpG binding proteins encoded in … against mutation, the
methyl-CpG binding proteins could … We will review the function of methyl-CpG binding proteins in …

Mechanism of transcriptional regulation by methyl-CpG binding protein MBD1

N Fujita, N Shimotake, I Ohki, T Chiba… - … and cellular biology, 2000 - Am Soc Microbiol
… To investigate the function of MBD1, we utilized promoter-associated CpG islands from human
genes, imprintedSNRPN (Citation34), and tumor suppressor p16as described previously (…