… developmental stages, exist on specific loci. Sites of DNA methylation are occupied by various
proteins, including methyl-CpG … methyltransferases, and methyl-CpG binding proteins in …

… for the neurological developmental disorder Rett Syndrome … at least some vertebrates retain
a requirement for a subset of … both these organisms, this requirement is not likely to result …

… methyl-CpGs. The knock-down of Kaiso leads to premature zygotic gene activation and
subsequent developmental … The requirement for DNA methylation in the embryonic and postnatal …

… , however, exhibited developmental defects whose severity was … Strikingly, the mouse DNA
methyltransferase is also required … specific binding to symmetrical methyl-CpG in a variety of …

… as expression of CpG island-containing ‘tissuespecific’ genes, developmental genes expressed
in a … that the expression of two copies of this gene is required in both males and females. …

… high density of CpGs. These are tissue- or developmentally dependent genes regulated by
… cells of the embryo to correctly express genes required for development and survival of the …

… called DNA-methyl-binding domain proteins (MBD1-4) or methyl CpG-binding proteins (…
However, special attention is required to the selection of the antibody regarding its specificity…

… Subsequent deletion analyses defined the region of MeCP2 required for binding to … premature
transcription of many genes and to developmental arrest and apoptosis. This phenotype is …

… of biological functions, including an essential developmental role in the reprogramming of
… DNA methylation requirements of specific non-imprinted loci in association with DNA methyl …

… The number and variety of proteins containing methyl-CpG binding domains (MBDs) that
are encoded in animal genomes also varies, with a general correlation between the extent of …