DNA demethylation
AP Wolffe, PL Jones, PA Wade - Proceedings of the …, 1999 - National Acad Sciences
… This issue has now been brought into sharper focus by the recent reports of a mammalian
protein with specific demethylase activity for methyl CpG dinucleotides (36), together with a …
protein with specific demethylase activity for methyl CpG dinucleotides (36), together with a …
[HTML][HTML] DNA methylation and methyl-CpG binding proteins: developmental requirements and function
O Bogdanović, GJC Veenstra - Chromosoma, 2009 - Springer
… are occupied by various proteins, including methyl-CpG binding … of DNA methylation, DNA
methyltransferases, and methyl-CpG … DNA methylation makes an essential and versatile …
methyltransferases, and methyl-CpG … DNA methylation makes an essential and versatile …
The methyl-CpG binding domain and the evolving role of DNA methylation in animals
B Hendrich, S Tweedie - TRENDS in Genetics, 2003 - cell.com
… DNA methylation-mediated silencing, and to protect against extensive mutation, there was
also a coordinate increase in the number and diversity of methyl-CpG … the methyl-CpG binding …
also a coordinate increase in the number and diversity of methyl-CpG … the methyl-CpG binding …
[PDF][PDF] The methyl-CpG-binding protein MBD7 facilitates active DNA demethylation to limit DNA hyper-methylation and transcriptional gene silencing
… limit the spread of DNA methylation by promoting active DNA demethylation. Active DNA
demethylation is also necessary for pruning the DNA methylation landscape of many TEs and is …
demethylation is also necessary for pruning the DNA methylation landscape of many TEs and is …
Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl‐CpG binding protein.
J Boyes, A Bird - The EMBO journal, 1992 - embopress.org
… by co-transfection of methylated competitor DNA, suggesting that … methyl-CpG binding
protein. We decided therefore to study further the effect of DNA methylation on transcription of CpG…
protein. We decided therefore to study further the effect of DNA methylation on transcription of CpG…
DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
J Boyes, A Bird - Cell, 1991 - cell.com
We have studied the mechanism by which DNA methyiation inhibits transcription both in ceil-free
nuclear extracts and in the living ceil. Repression of transcription in vitro for four …
nuclear extracts and in the living ceil. Repression of transcription in vitro for four …
… of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG …
… However, DNA methylation patterns are dynamic in nature and vary during development …
The cycle of early embryonic demethylation followed DNA methylation primarily occurs at CpG …
The cycle of early embryonic demethylation followed DNA methylation primarily occurs at CpG …
[HTML][HTML] The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation
… that MeCP2 facilitates H3 Lys 9 methylation of the H19 gene, a … DNA methylation and
histone methylation and thus reinforce the repressive function of these two distinct methylation …
histone methylation and thus reinforce the repressive function of these two distinct methylation …
Expression of mRNA for DNA methyltransferases and methyl-CpG–binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions …
Y Saito, Y Kanai, M Sakamoto, H Saito, H Ishii… - Hepatology, 2001 - Elsevier
… level of DNA methyltransferases may contribute to DNA methylation patterns in HCCs,
we analyzed the DNA methylation status on 7 type C CpG islands in the same cohort. DNA …
we analyzed the DNA methylation status on 7 type C CpG islands in the same cohort. DNA …
Methyl-CpG-binding domain protein MBD7 is required for active DNA demethylation in Arabidopsis
… Although researchers have established that DNA methylation and active demethylation …
DNA demethylation and antisilencing of the genomic loci with high densities of DNA methylation …
DNA demethylation and antisilencing of the genomic loci with high densities of DNA methylation …
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