Methyl-CpG-binding domain protein MBD7 is required for active DNA demethylation in Arabidopsis
… Although researchers have established that DNA methylation and active demethylation …
DNA demethylation and antisilencing of the genomic loci with high densities of DNA methylation …
DNA demethylation and antisilencing of the genomic loci with high densities of DNA methylation …
Mechanisms of DNA methylation, methyl-CpG recognition, and demethylation in mammals
X Cheng, H Hashimoto, JR Horton, X Zhang - Handbook of epigenetics, 2011 - Elsevier
… DNA methylation and histone modifications are intricately connected with each other … DNA
methylation profiles suggest that DNA methylation is better correlated with histone methylation …
methylation profiles suggest that DNA methylation is better correlated with histone methylation …
[HTML][HTML] Regulation of Active DNA Demethylation by a Methyl-CpG-Binding Domain Protein in Arabidopsis thaliana
… They are believed to function as an interpreter of DNA methylation … methyl-CpG-binding
activity and function in targeting of maintenance DNA methylation machinery, H3K9 methylation, …
activity and function in targeting of maintenance DNA methylation machinery, H3K9 methylation, …
[HTML][HTML] Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression
N Fujita, S Watanabe, T Ichimura, S Tsuruzoe… - Journal of Biological …, 2003 - ASBMB
… In this study, we show that H3 (Lys-9) methylase Suv39h1 and the methyl lysine-binding …
to methylated DNA regions. We discuss the possible pathway from DNA methylation to the …
to methylated DNA regions. We discuss the possible pathway from DNA methylation to the …
[HTML][HTML] N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso
HG Yoon, DW Chan, AB Reynolds, J Qin, J Wong - Molecular cell, 2003 - cell.com
… consequences of DNA methylation. Here we demonstrate that Kaiso, a methyl CpG binding
… In vitro, the Kaiso/N-CoR complex binds specific CpG-rich sequences in a methylation-…
… In vitro, the Kaiso/N-CoR complex binds specific CpG-rich sequences in a methylation-…
Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer
… In this study, we demonstrated a causal role for MBD2 in facilitation of DNA methylation
principally at aberrantly hypermethylated CpG islands and CpG shores and regulatory regions in …
principally at aberrantly hypermethylated CpG islands and CpG shores and regulatory regions in …
A mammalian protein with specific demethylase activity for mCpG DNA
SK Bhattacharya, S Ramchandani, N Cervoni, M Szyf - Nature, 1999 - nature.com
… The discovery of this DNA demethylase should provide a … analysis of the role of DNA
methylation and demethylation. … subjected demethylase-treated DNA to remethylation with the …
methylation and demethylation. … subjected demethylase-treated DNA to remethylation with the …
[HTML][HTML] DNA methylation and demethylation in mammals
… , a wave of global de novo methylation re-establishes the DNA methylation patterns that will
be maintained, in large part, in somatic tissues. Genome-wide demethylation also occurs in …
be maintained, in large part, in somatic tissues. Genome-wide demethylation also occurs in …
Biological functions of methyl-CpG-binding proteins
PA Defossez, I Stancheva - Progress in molecular biology and translational …, 2011 - Elsevier
… of CpG dinucleotides, while in plants DNA methylation can be found at CpG as well as non-CpG
… with the exception of stretches of DNA 500–2000 bp long known as CpG islands.1, 2, 3 …
… with the exception of stretches of DNA 500–2000 bp long known as CpG islands.1, 2, 3 …
Potential role of DNA methylation as a facilitator of target search processes for transcription factors through interplay with methyl-CpG-binding proteins
CA Kemme, R Marquez, RH Luu… - Nucleic acids …, 2017 - academic.oup.com
… MBD, when it is challenged with methylated CpG and unmethylated CpG sites within Egr-1
decoys. Our data demonstrate that DNA methylation of decoys accelerates Egr-1–target …
decoys. Our data demonstrate that DNA methylation of decoys accelerates Egr-1–target …