… Our findings indicate that DNA methylation is important in maintaining cellular genomic …
methylation, genomic stability and CNS functions. To understand the function of DNA methylation …

… regulate gene expression, while DNA repair ensures that those … DNA deaminase AID can
initiate DNA demethylation. In vitro, AID initiated targeted DNA demethylation of methyl CpGs …

… of active DNA demethylation. We then focus on the role of active DNA demethylation in diverse
… Finally, we discuss future directions of research in the area of active DNA demethylation. …

… by which DNA methylation is targeted to specific regions of the genome and interpreted by
methyl-CpG-binding proteins. Recent studies have illuminated the role of DNA methylation in …

… the mechanisms linking histone methylation and DNA methylation in mammalian cells. The
… DNA methylation profiles suggest that DNA methylation is correlated to histone methylation …

… DNA methylation, or the covalent addition of a methyl group to cytosine within the context
of the CpG … factor binding or the recruitment of methyl-binding proteins and their associated …

… fully unmodified DNA and are essential for establishment of DNA methylation patterns during
… levels of DNA methylation are depleted of CpGs due to the frequent deamination of methyl-…

… DNA methylation is assessed by massively parallel sequencing of methylation enriched
DNA … The applied method is based on the use of MeCP2, a member of the methyl-CpG-binding …

… DNA methylation, while a further wave of DNA demethylation … of DNA demethylation, through
inhibition of DNMTs and DNA … In fully differentiated somatic cells, active DNA demethylation …

… DNA demethylating enzymes has led to controversial results. The protein MBD2 (methyl CpG
… responsible for global DNA demethylation. It was demonstrated that MBD2 is a processive …